...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Medical science monitor : >Combination of diet, exercise and intermittent treatment of cimetidine on body weight and maintenance of weight loss. A 42 months follow-up study
【24h】

Combination of diet, exercise and intermittent treatment of cimetidine on body weight and maintenance of weight loss. A 42 months follow-up study

机译：饮食，运动和西咪替丁的间歇治疗相结合，可以减轻体重并保持体重减轻。 42个月的随访研究

获取原文
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: The aim of the study was to investigate the long term effect of diet, exercise and intermittent treatment of cimetidine on body weight and maintenance of weight lost during treatment.Material and methods: Fifty women and five men who had completed a 8 week randomized double-blind, placebo-controlled trial of cimetidine for weight loss were invited to participate in an open, non-randomized follow-up study of 42 months. The study was designed to compare weight loss and/or weight gain in subjects who, dependent on their level of motivation, volunteered to participate in an intervention or non-intervention group. In the intervention group the subjects were treated with cimetidine for 8 weeks twice a year, followed a diet restriction and performed regular exercise. In the non-intervention group the subjects had no behavioral treatment. Twenty two subjects volunteered to participate in the intervention program whereas 33 subjects volunteered to participate in the non-intervention group.Results: In the intervention group, non-significant reductions in body weight (1.9±5.5 kg), BMI (0.6±1.7 kg/m2), body fat% (1.7±2.9) and waist circumference (2.1±5.9 cm) were found. In the non-intervention group there was a significant increase in body weight (7.5±5.3 kg), BMI (2.6±1.8 kg/m2), body fat% (3.0±3.3) and waist circumference (6.7±5.1 cm). Among the group of subjects initially treated with cimetidine for 8 weeks and who followed a subsequent intervention of additional 42 months (n=16), there was a 15.1% weight loss. Among the group initially treated with placebo for 8 weeks and who volunteered to participate in the non-intervention group (n=22), there was a weight gain of 8.6%. In conclusion, the combination of diet restriction, regular exercise and intermittent treatment of cimetidine appears to have long term effects on body weight and maintenance of weight loss.
机译：前言：本研究的目的是研究饮食，运动和间断性西咪替丁对体重的长期影响以及治疗期间体重减轻的维持。材料与方法：50名女性和5名男性完成了为期8周的随机分组西米替丁减肥的双盲，安慰剂对照试验被邀请参加一项为期42个月的开放，非随机随访研究。该研究旨在比较自愿性参与干预或非干预组的受试者的体重减轻和/或体重增加。在干预组中，受试者每年两次接受西咪替丁治疗8周，然后节食，并进行定期运动。在非干预组中，受试者没有行为治疗。 22名受试者自愿参加了干预计划，而33名受试者自愿参加了非干预组。结果：在干预组中，体重（1.9±5.5 kg），BMI（0.6±1.7 kg）无明显减轻。 / m2），发现体内脂肪百分比（1.7±2.9）和腰围（2.1±5.9 cm）。在非干预组中，体重（7.5±5.3 kg），BMI（2.6±1.8 kg / m2），体脂％（3.0±3.3）和腰围（6.7±5.1 cm）显着增加。在最初接受西咪替丁治疗8周并随后再干预42个月（n = 16）的一组受试者中，体重减轻了15.1％。在最初接受安慰剂治疗8周并自愿参加非干预组的患者中（n = 22），体重增加了8.6％。总之，限制饮食，定期运动和间断使用西咪替丁似乎对体重和维持体重减轻具有长期影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号