...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Medical science monitor : >Relationship of serum immunoglobulin and IgG subclass levels to race, ethnicity and behavioral characteristics in HIV infection
【24h】

Relationship of serum immunoglobulin and IgG subclass levels to race, ethnicity and behavioral characteristics in HIV infection

机译：血清免疫球蛋白和IgG亚类水平与HIV感染中的种族，种族和行为特征的关系

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: To determine whether demographic and behavioral factors affectimmunoglobulin regulation in HIV infection, we studied injection drug users, women, and minority ethnicand racial groups with and without HIV infection. Material/Methods: A prospective cross-sectional studyof ambulatory persons with or at risk for HIV infection was conducted. We enrolled 48 injection drugusers (IDUs) and 43 non-IDUs seropositive for HIV and 22 seronegative at-risk individuals in the Bronx,New York City. Sixteen HIV-seronegative, non-IDUs controls were also studied. Total serum immunoglobulinlevels, IgG subclasses and lymphocyte phenotypes were measured. Results: Serum IgG, IgA, IgG[sub]1[/sub] and IgG(3)were increased in all stages of HIV infection controlling for injection drug use, gender, race and age(p0.05). Serum IgM levels were significantly decreased in HIV seropositives compared to HIV seronegatives(p
机译：背景：为了确定人口统计学和行为因素是否会影响HIV感染中免疫球蛋白的调节，我们研究了注射吸毒者，妇女以及有无HIV感染的少数民族和种族群体。材料/方法：对患有或有感染HIV风险的非卧床者进行了前瞻性横断面研究。我们在纽约市布朗克斯市招募了48名注射吸毒者（IDU）和43名非HIV血清阳性的非吸毒者和22名血清阴性的高危人群。还研究了16个HIV血清反应阴性，非毒品使用者的对照。测量血清总免疫球蛋白水平，IgG亚类和淋巴细胞表型。结果：在控制注射药物使用，性别，种族和年龄的HIV感染的所有阶段中，血清IgG，IgA，IgG [1 / sub]和IgG（3）均升高（p0.05）。与HIV血清阴性药相比，HIV血清阳性药的血清IgM水平显着降低（p

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号