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首页> 外文期刊>Medical science monitor : >Asymptomatic atherosclerosis and myocardial infarction. Risk modified by ability to adapt to stressful situations. Results from prospective cohort study “Men born in 1914”, Malmö, Sweden
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Asymptomatic atherosclerosis and myocardial infarction. Risk modified by ability to adapt to stressful situations. Results from prospective cohort study “Men born in 1914”, Malmö, Sweden

机译：无症状的动脉粥样硬化和心肌梗塞。适应压力的能力可以改变风险。瑞典马尔默前瞻性队列研究“ 1914年出生的男人”的研究结果

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Background:The purpose of this study was to investigate whether different behaviors in a stressful situation modify the risk of atherosclerosis in association with a myocardial infarction, cardiovascular mortality, and all-cause mortality. Many individuals have atherosclerotic changes in their arteries but may never experience any symptoms nor develop cardiovascular disease. A myocardial infarction is caused by a disruption of a vulnerable atherosclerotic plaque. The mechanisms that trigger these events are not fully understood, but among the proposed agents is psychological stress. A differential in risk exposure could be expected since individuals differ in their ability to cope with stressful situations.Material/Methods: In the prospective cohort study “Men born in 1914”, atherosclerosis was noninvasively studied in the peripheral, carotid, and coronary arteries at a baseline examination in 1982/83. The serial Color Word Test, which is a semi-experimental way to assess how individuals adapt in a stressful situation, was administered at the same examination. Participants were followed-up regarding incidence of myocardial infarction and mortality until December 31 1996.Results: Atherosclerosis was associated with an increased risk of myocardial infarction (relative risk (RR) 2.96; 95% confidence interval (CI) 1.52 to 5.74) and cardiovascular mortality (RR 3.31; 95% CI 2.08 to 5.28) during follow-up only among the men who showed maladaptive behavior. No excess risk could be established in men with an adaptive behavior pattern.Conclusions: The serial Color Word Test can assist in identifying men at high cardiovascular risk.
机译：背景：本研究的目的是调查在应激状态下的不同行为是否会改变与心肌梗塞，心血管疾病死亡率和全因死亡率相关的动脉粥样硬化风险。许多人的动脉有动脉粥样硬化改变，但可能从未出现任何症状或发展为心血管疾病。心肌梗塞是由易损动脉粥样硬化斑块的破坏引起的。引发这些事件的机制尚不完全清楚，但提出的因素中有心理压力。材料/方法：在前瞻性队列研究“ 1914年出生的人”中，对动脉粥样硬化的研究无创，涉及外周动脉，颈动脉和冠状动脉，因此预期会有不同的风险暴露。在1982/83年进行了基线检查。在同一项考试中进行了连续彩色单词测试，这是一种评估个人如何适应压力状况的半实验方法。直到1996年12月31日为止，随访参与者的心肌梗塞发生率和死亡率。结果：动脉粥样硬化与心肌梗塞风险增加（相对风险（RR）2.96; 95％置信区间（CI）1.52至5.74）和心血管疾病相关仅在表现出适应不良行为的男性中随访期间的死亡率（RR 3.31; 95％CI 2.08至5.28）。结论：连续彩色单词测试可以帮助识别高心血管风险的男性。

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