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Adding Doppler Ultrasonography to the Follow-Up of Patients with Vasospastic Disorder Improves Objectivity

机译：在血管痉挛性疾病患者的随访中增加多普勒超声检查可提高客观性

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Background Assessing therapeutic efficacy and patient satisfaction objectively and quantitatively has always been a problem in patients with vasospastic disorders. We aimed to present the additive value of ultrasonographic assessment of peripheral arteries secondary to cold stimulation, as a test for treatment efficacy during follow-up. Material and Methods Arterial blood flow rates were measured from radial artery with Doppler USG in patients who presented to our department with vasospastic disorders. Ultrasonography was performed at the following intervals; before cold stimulation and at 5th, 10th, 15th, 20th minutes of cold stimulation. Patients were controlled by repeat cold stimulation test and Doppler US at the 2nd month of the treatment. Results were analyzed with SPSS for Mac 20.0 package program. Results We enrolled 46 patients in the study. All patients were male and mean age was 22.3±2.17 years. Most common symptoms were cyanosis and coldness. There were statistically significant differences between pre-treatment and post-treatment arterial blood flow rates at each measurement time point (p0.05). On post-treatment values, there were 10.04±0.78 cm/s increase in 5th minute, 6.25±1.39 cm/s in 10th minute, 6.43±2.13 cm/s in 15th minute, and 6.38±1.86 cm/s in 20th minute measurements. All increases at the 5 time points were statistically meaningful when compared to their pre-treatment corresponding time points (p<0.001). Conclusions Doppler flowmetry added to standard cold stimulation test for evaluating the patients with vasospastic disorders provides better and more objective results when compared to the patient-oriented subjective scoring systems.
机译：背景技术客观和定量地评估治疗效果和患者满意度一直是血管痉挛性疾病患者的难题。我们的目的是介绍超声刺激对冷刺激继发的周围动脉超声评估的附加值，以作为随访期间治疗效果的测试。材料和方法对就诊为血管痉挛性疾病的患者，使用多普勒USG测量radial动脉的动脉血流量。超声检查按以下间隔进行：在冷刺激之前和冷刺激的第5、10、15、20分钟时。在治疗的第二个月，通过重复的冷刺激试验和多普勒超声对患者进行控制。结果使用SPSS for Mac 20.0软件包程序进行了分析。结果我们招募了46名患者。所有患者均为男性，平均年龄为22.3±2.17岁。最常见的症状是发osis和发冷。在每个测量时间点，治疗前和治疗后动脉血流量之间存在统计学上的显着差异（p0.05）。在处理后的值上，第5分钟增加了10.04±0.78 cm / s，第10分钟增加了6.25±1.39 cm / s，第15分钟增加了6.43±2.13 cm / s，第20分钟测量了6.38±1.86 cm / s 。与治疗前的相应时间点相比，这5个时间点的所有增加均具有统计学意义（p <0.001）。结论与针对患者的主观评分系统相比，多普勒血流仪在标准冷刺激试验中添加了用于评估血管痉挛性疾病的患者，可提供更好，更客观的结果。

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