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Comparative study of the retinal nerve fibre layer thickness performed with optical coherence tomography and GDx scanning laser polarimetry in patients with primary open-angle glaucoma

机译:光学相干断层扫描和GDx扫描激光偏光法对原发性开角型青光眼患者视网膜神经纤维层厚度的比较研究

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Background:We compared the parameters of retinal nerve fibre layer in patients with advanced glaucoma with the use of different OCT (Optical Coherence Tomograph) devices in relation to analogical measurements performed with GDx VCC (Nerve Fiber Analyzer with Variable Corneal Compensation) scanning laser polarimetry.Material/Methods:Study subjects had advanced primary open-angle glaucoma, previously treated conservatively, diagnosed and confirmed by additional examinations (visual field, ophthalmoscopy of optic nerve, gonioscopy), A total of 10 patients were enrolled (9 women and 1 man), aged 18–70 years of age. Nineteen eyes with advanced glaucomatous neuropathy were examined. 1) Performing a threshold perimetry Octopus, G2 strategy and ophthalmoscopy of optic nerve to confirm the presence of advanced primary open-angle glaucoma; 2) performing a GDx VCC scanning laser polarimetry of retinal nerve fibre layer; 3) measuring the retinal nerve fibre layer thickness with 3 different optical coherence tomographs.Results:The parameters of the retinal nerve fibre layer thickness are highly correlated between the GDx and OCT Stratus and 3D OCT-1000 devices in mean retinal nerve fibre layer thickness, retinal nerve fibre layer thickness in the upper sector, and correlation of NFI (GDx) with mean retinal nerve fibre layer thickness in OCT examinations. Absolute values of the retinal nerve fibre layer thickness (measured in μm) differ significantly between GDx and all OCT devices.Conclusions:Examination with OCT devices is a sensitive diagnostic method of glaucoma, with good correlation with the results of GDx scanning laser polarimetry of the patients.
机译:背景:我们使用GDx VCC(具有可变角膜补偿的神经纤维分析仪)扫描激光偏振仪对使用类似OCT(光学相干断层扫描仪)设备进行的模拟测量,对晚期青光眼患者的视网膜神经纤维层参数进行了比较。材料/方法:研究对象患有晚期原发性开角型青光眼,先前接受过保守治疗,通过其他检查(视野,视神经检眼镜,斜视镜)进行了诊断和确诊,共入组10例患者(9名女性和1名男性) ,年龄在18-70岁之间。检查了19只患有晚期青光眼神经病的眼睛。 1)进行阈值视野检查,章鱼,G2策略和视神经的检眼镜检查,以确认存在晚期原发性开角型青光眼; 2)对视网膜神经纤维层进行GDx VCC扫描激光偏振法; 3)用3种不同的光学相干断层扫描仪测量视网膜神经纤维层厚度。结果:GDx和OCT Stratus与3D OCT-1000装置之间的视网膜神经纤维层厚度参数与平均视网膜神经纤维层厚度高度相关,上段视网膜神经纤维层厚度,以及OCT检查中NFI(GDx)与平均视网膜神经纤维层厚度的相关性。结论GDx与所有OCT设备的视网膜神经纤维层厚度的绝对值(以μm为单位)存在显着差异。结论:OCT设备的检查是一种灵敏的青光眼诊断方法,与GDx扫描激光偏振仪的结果有很好的相关性。耐心。

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