Carbapenem Resistance: A Review

Francis S. Codjoe; Eric S. Donkor

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Carbapenem Resistance: A Review

机译：耐碳青霉烯：综述

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Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae , Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by transferable carbapenemase-encoding genes. This type of resistance genes are already widespread in certain parts of the world, particularly Europe, Asia and South America, while the situation in other places such as sub-Saharan Africa is not well documented. In this paper, we provide an in-depth review of carbapenem resistance providing up-to-date information on the subject.

机译：碳青霉烯耐药性是全球主要且持续存在的公共卫生问题。它主要发生在革兰氏阴性病原体中，例如肺炎克雷伯菌，铜绿假单胞菌和鲍曼不动杆菌，并且可能是固有的或由可转移的碳青霉烯酶编码基因介导。这种抗药性基因已经在世界某些地区广泛传播，特别是在欧洲，亚洲和南美，而诸如撒哈拉以南非洲等其他地区的情况却没有得到充分记录。在本文中，我们提供了对碳青霉烯耐药性的深入综述，提供了有关该主题的最新信息。

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《Medical Sciences》 |2018年第1期|共28页
作者
Francis S. Codjoe; Eric S. Donkor;
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中图分类临床医学;
关键词
Gram negative bacillicarbapenemsantibiotic resistancecarbapenemases;

机译：革兰氏阴性菌;

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1. Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis [J] . Righi Elda, Peri Anna Maria, Harris Patrick N. A., The Journal of Antimicrobial Chemotherapy . 2017,第3期

机译：中性患者患者耐药性的全局患病率及死亡率和肉豆蔻蛋白酶用途：系统评价和荟萃分析
2. Prevalence of carbapenem resistance and carbapenemase production among Enterobacteriaceae isolated from urine in the UK: results of the UK infection-Carbapenem Resistance Evaluation Surveillance Trial (iCREST-UK) [J] . NeilWoodford, LiXu-McCrae, ShazadMushtaq, The Journal of Antimicrobial Chemotherapy . 2018,第3期

机译：英国尿液中肠杆菌区抗胰岛抗性和碳碱蛋白酶生产的患病率：英国感染 - 碳抗抵抗力评价监测试验的结果（ICREST-UK）
3. Increasing Resistance to Extended-Spectrum Cephalosporins, Fluoroquinolone, and Carbapenem in Gram-Negative Bacilli and the Emergence of Carbapenem Non-Susceptibility in Klebsiella pneumoniae: Analysis of Korean Antimicrobial Resistance Monitoring System (KARMS) Data From 2013 to 2015 [J] . Annals of laboratory medicine. . 2017,第3期

机译：对革兰氏阴性杆菌中广谱头孢菌素，氟喹诺酮和碳青霉烯类药物的耐药性增加以及肺炎克雷伯菌中碳青霉烯类药物的不易感性：2013年至2015年韩国抗菌素耐药性监测系统（KARMS）数据分析
4. A scoping review of the peer-reviewed literature in human populations and in vitro for potential non-antimicrobial interventions to reduce antimicrobial resistance in cattle [C] . V.R. Fajt, C.R Murphy, R Wickwire, Annual Conference of the American^Association^of^Bovine^Practitioners. . 2014

机译：对人口的同伴审查文学的范围审查，对潜在的非抗微生物干预措施降低牛的抗微生物抗药性
5. Detection of carbapenem-resistant bacteria in drinking water and potential for inter-genus transfer of resistance factors. [D] . Tanner, Windy Dawn. 2014

机译：检测饮用水中对碳青霉烯类耐药的细菌以及耐药因子在属间转移的潜力。
6. Increasing Resistance to Extended-Spectrum Cephalosporins Fluoroquinolone and Carbapenem in Gram-Negative Bacilli and the Emergence of Carbapenem Non-Susceptibility in Klebsiella pneumoniae: Analysis of Korean Antimicrobial Resistance Monitoring System (KARMS) Data From 2013 to 2015 [O] . Dokyun Kim, Ji Young Ahn, Chae Hoon Lee, 2017

机译：革兰氏阴性芽孢杆菌对广谱头孢菌素氟喹诺酮和碳青霉烯类药物的耐药性增加以及肺炎克雷伯菌中碳青霉烯类药物的不易感性：2013年至2015年韩国抗菌药物耐药性监测系统（KARMS）数据分析
7. Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis [O] . Righi, Elda, Peri, Anna Maria, Harris, Patrick N. A., 2017

机译：中性粒细胞减少症患者对碳青霉烯耐药的全球患病率及其与死亡率和碳青霉烯使用的关联：系统评价和荟萃分析
8. Carbapenem Susceptibility Testing Errors Using Three Automated Systems, Disk Diffusion, Etest, and Broth Microdilution and Carbapenem Resistance Genes in Isolates of Acinetobacter baumannii-calcoaceticus Complex. [R] . Markelz, A. E., Mende, K., Murray, C. K., 2011

机译：使用三种自动化系统，磁盘扩散，Etest和肉汤微量稀释和碳青霉烯类抗性基因在鲍曼不动杆菌 - 醋酸钙不动杆菌复合物的分离物中的碳青霉烯类易感性测试错误。

Carbapenem Resistance: A Review

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