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Is methane a new therapeutic gas?

机译：甲烷是新的治疗气体吗？

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Background Methane is an attractive fuel. Biologically, methanogens in the colon can use carbon dioxide and hydrogen to produce methane as a by-product. It was previously considered that methane is not utilized by humans. However, in a recent study, results demonstrated that methane could exert anti-inflammatory effects in a dog small intestinal ischemia-reperfusion model. Point of view Actually, the bioactivity of methane has been investigated in gastrointestinal diseases, but the exact mechanism underlying the anti-inflammatory effects is required to be further elucidated. Methane can cross the membrane and is easy to collect due to its abundance in natural gas. Although methane is flammable, saline rich in methane can be prepared for clinical use. These seem to be good news in application of methane as a therapeutic gas. Conclusion Several problems should be resolved before its wide application in clinical practice.
机译：背景技术甲烷是一种有吸引力的燃料。从生物学上讲，结肠中的产甲烷菌可以利用二氧化碳和氢气产生副产甲烷。以前认为，人类没有利用甲烷。然而，在最近的一项研究中，结果表明甲烷可以在犬小肠缺血-再灌注模型中发挥抗炎作用。观点实际上，已经在胃肠道疾病中研究了甲烷的生物活性，但是需要进一步阐明其抗炎作用的确切机制。甲烷可以穿过膜，并且由于其在天然气中的丰度而易于收集。尽管甲烷是易燃的，但是可以准备富含甲烷的盐水以用于临床。这些在将甲烷用作治疗气体方面似乎是个好消息。结论在将其广泛应用于临床之前应解决一些问题。

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