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Potential application of hydrogen in traumatic and surgical brain injury, stroke and neonatal hypoxia-ischemia

机译:氢在创伤性和外科性脑损伤,中风和新生儿缺氧缺血中的潜在应用

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This article summarized findings of current preclinical studies that implemented hydrogen administration, either in the gas or liquid form, as treatment application for neurological disorders including traumatic brain injury (TBI), surgically induced brain injury (SBI), stroke, and neonatal hypoxic-ischemic brain insult (HI). Most reviewed studies demonstrated neuroprotective effects of hydrogen administration. Even though anti-oxidative potentials have been reported in several studies, further neuroprotective mechanisms of hydrogen therapy remain to be elucidated. Hydrogen may serve as an adjunct treatment for neurological disorders.
机译:本文总结了当前临床前研究的结果,这些研究以气体或液体形式进行氢气施用,作为神经系统疾病的治疗应用,包括颅脑外伤(TBI),外科手术性脑外伤(SBI),中风和新生儿缺氧缺血脑损伤(HI)。大多数审查的研究表明氢给药的神经保护作用。即使在几项研究中已经报道了抗氧化的潜力,氢治疗的其他神经保护机制仍有待阐明。氢可以作为神经系统疾病的辅助治疗。

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