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Hodgkin lymphoma involving the tonsil misdiagnosed as tonsillar carcinoma: A case report and review of the literature

机译：涉及扁桃体的霍奇金淋巴瘤被误诊为扁桃体癌：一例报道并文献复习

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Rationale: Primary Hodgkin lymphoma (HL) involving the tonsil is extremely rare. Only about 20 such cases with verification of biopsy and immunohistochemistry have been reported. Because of its rarity and unremarkable clinical presentation, a timely correct diagnosis is very challenging. Patient concerns: A 43-year-old man complained left tonsillar enlargement and painless masses in left neck, with night sweat. The clinical examination found a marked tonsillar asymmetry, with an enlarged left tonsil and ipsilateral cervical lymphadenopathy and a normal right tonsil . Diagnosis: The patient was initially regarded as tonsillar lymphoepithelial carcinoma. Interventions: The patient received a resection of left tonsil and left cervical masses and then was definitively diagnosed as HL (IIEB). He was managed by 6 cycles of chemotherapy (adriamycin, bleomycin, vinblastine, and dacarbazine) and radiotherapy to the Waldeyer ring. Outcomes: The patient has been disease free for more than 3 years after diagnosis. Lessons: As the reason of an extreme rare occurrence of HL involving the tonsil , doctors can easily misdiagnose the disease as tonsillar lymphoepithelial carcinoma. This case serves as a reminder important role of biopsy.
机译：理由：涉及扁桃体的原发性霍奇金淋巴瘤（HL）非常罕见。仅有约20例经过活检和免疫组织化学验证的病例。由于其稀有性和不明显的临床表现，及时正确的诊断非常具有挑战性。病人担忧：一名43岁的男子抱怨左扁桃体肿大，左颈部无痛性肿块，伴有盗汗。临床检查发现扁桃体明显不对称，左扁桃体增大，同侧颈淋巴结肿大，右扁桃体正常。诊断：该患者最初被认为是扁桃体淋巴上皮癌。干预措施：患者接受了左扁桃体和左宫颈肿块的切除，然后被明确诊断为HL（IIEB）。他接受了6个周期的化疗（阿霉素，博来霉素，长春碱和达卡巴嗪）和Waldeyer环放射治疗。结果：患者在诊断后已无疾病三年以上。经验教训：由于扁桃体极少发生HL，医生很容易将其误诊为扁桃体淋巴上皮癌。该病例提醒了活检的重要作用。

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