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Association of muscle strength with cardiovascular risk in Korean adults: Findings from the Korea National Health and Nutrition Examination Survey (KNHANES) VI to VII (2014–2016)

机译:韩国成年人的肌肉力量与心血管风险的关联:韩国国家健康与营养检查调查(KNHANES)六至七(2014-2016)的发现

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There are few existing studies that examine the association between muscle strength and cardiovascular disease (CVD) risk stratified by sex. Evaluation of the handgrip strength is a simple, quick, and inexpensive method to measure muscle strength . This study assessed the association of handgrip strength with the risk of CVD in the Korean general population. Data were derived from a subset of an ongoing nationally representative survey: the Korea National Health and Nutrition Examination Survey (KNHANES), 2014 to 2016, which included 8576 participants aged 40 to 79 years (men: 3807; women: 4769). Individual CVD risk was evaluated by calculating the atherosclerotic cardiovascular disease (ASCVD) risk score and the Framingham risk score (FRS) in subjects aged 40 to 79 years without prior CVD. Multivariate linear regression analysis revealed a significant inverse association (in both men and women) between relative handgrip strength and cardiovascular risk factors, including blood pressure, levels of fasting glucose and triglycerides, waist circumstance, FRS, high sensitivity C-reactive protein levels, and ASCVD risk. A significant positive association between relative handgrip and a low level of high density cholesterol levels in both men and women was identified. In both men and women, subjects in the lowest quartile of handgrip strength had an increased risk of CVD compared with those within the highest quartile (odds ratio range 2.05–3.03). The results of this study suggest that increased handgrip is associated with a lower degree of cardiovascular risk in both men and women. Longitudinal studies are needed to examine the association between muscle strength and cardiovascular risk.
机译:现有的研究很少研究按性别分层的肌肉力量与心血管疾病(CVD)风险之间的关系。握力的评估是一种简单,快速且廉价的测量肌肉力量的方法。这项研究评估了韩国普通人群中握力与CVD风险的关系。数据来自正在进行的全国代表性调查的一部分:2014年至2016年韩国国家健康与营养调查(KNHANES),其中包括8576名年龄在40至79岁之间的参与者(男性:3807;女性:4769)。通过计算40至79岁未曾进行过CVD的受试者的动脉粥样硬化性心血管疾病(ASCVD)风险评分和Framingham风险评分(FRS)来评估个体CVD风险。多元线性回归分析显示,相对握力和心血管危险因素之间存在显着的负相关关系(包括男性和女性),包括血压,空腹血糖和甘油三酸酯水平,腰围情况,FRS,高敏C反应蛋白水平以及ASCVD风险。在男性和女性中,相对手柄和低水平的高密度胆固醇水平之间存在显着的正相关关系。在男性和女性中,握力最低的四分之一受试者与最高四分之一的受试者相比,患CVD的风险增加(优势比范围为2.05-3.03)。这项研究的结果表明,提高握力与降低男性和女性的心血管风险有关。需要进行纵向研究以检查肌肉力量与心血管风险之间的关系。

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