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首页> 外文期刊>European Journal of Translational Myology >Dynamic cardiomyoplasty. Clinical follow-up in Argentina
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Dynamic cardiomyoplasty. Clinical follow-up in Argentina

机译:动态心肌成形术。阿根廷的临床随访

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The aim of the present study is to evaluate results obtained after applying dynamic cardiomyoplasty to patients with dilated cardiomyopathy and severe ventricular dysfunction (Functional Class III-IV, New York Heart Association).A dynamic cardiomyoplasty procedure was performed in 15 patients with a mean age of 59.2 ± 6.4 years old. Despite the medical treatment with inhibitors of the converted enzyme or vasodilators, all of these patients required 2.2 ± 0.7 hospitalizations/patient/year owing to congestive heart failure in the year before dynamic cardiomioplasty was applied. In 8 patients the etiology of the cardiomyopathy was idiopathic, ischemic-necrotic in 6 and Chagas' disease in the other.Hemodynamic studies were done preoperatively in all patients and every six months postoperatively.Twelve patients had a follow-up for two years. The following values related to two-years evaluation improved significantly in comparison with baseline: functional class (1.7 ± 0.6 versus 3.06 ± 0.2); radionuclide left ventricular ejection fraction (29.7 ± 5% versus 23.6 ± 3%); fractional shortening (20.6 ± 5% versus 15.6 ± 4%). Walking test values increased from 332 ± 127 meters to 421 ± 102 meters. Left ventricular diastolic diameter remained unchanged (72.7 ± 7 mm versus 72.3 ± 8 mm).Improvement was observed in functional capacity and left ventricle systolic function parameters two years after cardiomyoplasty was applied.
机译:本研究的目的是评估对扩张型心肌病和严重心室功能不全的患者进行动态心肌成形术后获得的结果(功能性III-IV级,纽约心脏协会),对15名平均年龄的患者进行了动态心肌成形术59.2±6.4岁。尽管使用转化酶抑制剂或血管扩张药进行了药物治疗,但由于在应用动态心脏置换术前一年发生充血性心力衰竭,所有这些患者均需住院治疗2.2 / 0.7 /人/年。在8例患者中,心肌病的病因是特发性的,在6例中是缺血性坏死的,在另一例中是Chagas'病的。所有患者术前和术后每6个月进行血流动力学研究,其中12例接受了两年的随访。与两年评估相关的以下值与基线相比有显着改善:功能等级(1.7±0.6对3.06±0.2);放射性核素左心室射血分数(29.7±5%对23.6±3%);分数缩短(20.6±5%对15.6±4%)。步行测试值从332±127米增加到421±102米。左心室舒张期直径保持不变(72.7±7 mm对72.3±8 mm)。在应用心肌成形术两年后,观察到功能能力和左心室收缩功能参数的改善。

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