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首页> 外文期刊>Korean journal of radiology : >Natural History of Untreated Coronary Total Occlusions Revealed with Follow-Up Semi-Automated Quantitative Coronary CT Angiography: The Morphological Characteristics of Initial CT Predict Occlusion Shortening
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Natural History of Untreated Coronary Total Occlusions Revealed with Follow-Up Semi-Automated Quantitative Coronary CT Angiography: The Morphological Characteristics of Initial CT Predict Occlusion Shortening

机译：未治疗的冠状动脉总闭塞的自然史与后续半自动定量冠状动脉CT血管造影揭示：初始CT的形态学特征可预测闭塞缩短

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Objective To investigate the morphological changes of coronary chronic total occlusion (CTO) as determined by coronary computed tomography angiography (CCTA) follow-up using semi-automated quantitative analysis. Materials and Methods Thirty patients with 31 CTO lesions confirmed by invasive coronary angiography and baseline/follow-up CCTA were retrospectively included. CTOs were quantitatively analyzed by a semi-automated coronary plaque analysis software (Coronary Plaque Analysis, version 2.0, Siemens) after manually determining the lesion border. Recanalized lumen was defined as the linear-like enhanced opacity traversing the non-opacified occluded segment. Other parameters, such as total occlusion length, total occlusion volume, volume with low attenuation component ( Results Recanalized lumen was found within 48.4% (15/31) occlusions on the follow-up CCTA, compared to 45.2% (14/31) occlusions on the baseline CCTA. Eleven of 14 lesions (78.6%) with CT-visible recanalized lumen within CTOs had a shorter occlusion length on follow-up compared to only 3 of 17 lesions (17.6%) without CT-visible recanalized lumen (odds ratio, 17.1, p Conclusion Coronary computed tomography angiography enables non-invasive characterization of natural progression of untreated CTO lesions. Recanalized lumen within CTOs observed at baseline CCTA was associated with shortening of occlusion length on follow-up. Compared to their earlier stage, occlusions of later stage were presented with higher density of non-calcified components.
机译：目的探讨采用半自动定量分析方法通过冠状动脉计算机断层摄影血管造影术（CCTA）随访确定的冠状动脉慢性完全阻塞（CTO）的形态变化。资料与方法回顾性分析30例经侵入性冠状动脉造影和基线/随访CCTA确诊的31例CTO病变的患者。在手动确定病变边界后，通过半自动冠状动脉斑块分析软件（Coronary Plaque Analysis，版本2.0，Siemens）对CTO进行了定量分析。椎管再通管腔被定义为穿过非不透明闭塞节段的线性增强不透明度。其他参数，例如总咬合长度，总咬合体积，低衰减分量的体积（结果随访CCTA发现再通管腔在48.4％（15/31）咬合内，而45.2％（14/31）咬合CTOs内有CT可见小管腔的14个病变中有11个（78.6％）随访时闭塞长度短，而CT可见无小管腔的17个病变中只有3个（17.6％）。 ，17.1，p结论冠状动脉计算机断层血管造影术能够对未治疗的CTO病变的自然进展进行非侵入性表征，在基线CCTA观察到的CTO内再通管腔与随访时的闭塞长度缩短有关。后期出现较高密度的非钙化成分。

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