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首页> 外文期刊>Korean journal of radiology : >Quality of Life in Patients Treated with Percutaneous Laser Ablation for Non-Functioning Benign Thyroid Nodules: A Prospective Single-Center Study
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Quality of Life in Patients Treated with Percutaneous Laser Ablation for Non-Functioning Benign Thyroid Nodules: A Prospective Single-Center Study

机译：经皮激光消融治疗非功能性良性甲状腺结节患者的生活质量：一项前瞻性单中心研究

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Objective While many studies have reported that laser ablation (LA) for benign non-fuctioning thyroid nodules is efficacious in reducing nodular volume and neck symptoms, none have described changes in quality of life (QoL). The purpose of this study was to report post-LA changes in QoL in our cohort of patients. Materials and Methods Fourteen patients with benign thyroid nodules were involved in a prospective, single-center study and underwent a single session of LA. We evaluated the following: changes in nodule volume, thyroid function, and autoimmunity; adverse events during and after LA; changes in neck discomfort by means of a visual analogic scale (VAS) at one week and 1, 3, 6, and 12 months; and changes in QoL through the 13-scale Thyroid-specific Patient Reported Outcome (ThyPRO) questionnaire at 1, 3, 6, and 12 months. ThyPRO is a validated questionnaire for thyroid diseases, which consists of 13 scales with multiple-choice answers. They investigate several aspects of life that may be impaired by goiter-related compression symptoms, by esthetic alterations and by hypo- or hyperthyroidism. Results Nodule volume decrease was ?37 ± 23%, ?55 ± 22%, ?53 ± 25%, ?58 ± 25% ( p Conclusion Laser ablation is safe and effective in reducing nodule volume and neck symptoms; this is confirmed by improvements in the goiter scale, general score, and mean values of ThyPRO and in the VAS score.
机译：目的尽管许多研究报告说，良性非功能性甲状腺结节的激光消融（LA）可以有效减少结节体积和颈部症状，但尚无描述生活质量（QoL）改变的方法。这项研究的目的是报告我们患者队列中LA后的QoL变化。材料和方法14例甲状腺良性结节患者参加了一项前瞻性，单中心研究，并接受了一次LA评估。我们评估了以下内容：结节量，甲状腺功能和自身免疫的改变;洛杉矶期间和之后的不良事件; 1周，1、3、6和12个月时通过视觉类比量表（VAS）改变颈部不适感;并在1、3、6和12个月通过13份甲状腺特异性患者报告结果（ThyPRO）问卷调查QoL。 ThyPRO是一种经过验证的甲状腺疾病问卷，由13个量表和多项选择答案组成。他们研究了可能因甲状腺肿相关的压迫症状，美学改变以及甲状腺功能减退或亢进而受损的生活的几个方面。结果结节体积减少为？37±23％、? 55±22％、? 53±25％、? 58±25％（p结论激光消融可安全有效地减少结节体积和颈部症状;这已通过改善得到证实在甲状腺肿评分，总评分，ThyPRO平均值和VAS评分中。

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