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Treatment outcome of TB patients in a district of north India: a three year study

机译:印度北部某地区结核病患者的治疗结果:一项为期三年的研究

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Background Tuberculosis (TB), still remains a public health problem of great concern. It was estimated that 8.6 million people developed TB and 1.3 million died from it. India has the highest TB burden in the world. DOTS ensures high cure. Therefore the present study was planned to assess the outcome of DOTS treatment among pulmonary and extra pulmonary TB patients reporting at DOTS centers of the district Materials and methods: A record based study using the routine program data of Revised National Tuberculosis Control Programme was conducted in one of twenty two districts of state of Punjab, situated in northern India. Records of all the patients registered from 1 st January 2011 till 31 st December 2013 were analysed using descriptive statistics. The differences between proportions were compared using tests of significance. Results: A total of 2571 new cases of Tuberculosis were registered during the study period of three years, out of which 44.8%, 22.9% and 32.3% were diagnosed to be new smear positive, smear negative and suffering from Extra pulmonary tuberculosis (EPTB) and a total of 369 retreatment cases were registered. Cure rates were highest among patients suffering from EPTB when compared to those of smear positive and smear negative. The proportion of defaulters among smear positive failures was highest, followed by smear positive after default and lowest in smear positive relapses. Conclusion Cure rates were higher among EPTB cases whereas default rate was more among patients suffering from pulmonary TB. Therefore higher level of motivation of cases by health and non-health personnel is required as untreated or under treated pulmonary TB cases are responsible for transmission of the disease in the community. Default rates could be decreased by concrete efforts in the form of strict supervision and monitoring. DOI: http://dx.doi.org/10.3126je.v5i1.12376
机译:背景结核病(TB)仍然是人们非常关注的公共卫生问题。据估计,有860万人患有结核病,其中130万人死于结核病。印度是世界上结核病负担最高的国家。 DOTS可确保高度固化。因此,本研究计划用于评估在该地区DOTS中心报告的肺结核和肺外结核患者中DOTS治疗的结果。材料和方法:使用修订后的《国家结核病控制计划》的常规计划数据进行基于记录的研究位于印度北部的旁遮普邦二十二个州中的一个。使用描述性统计数据分析了2011年1月1日至2013年12月31日期间所有登记的患者的记录。使用显着性检验比较比例之间的差异。结果:在三年的研究期间,共登记了2571例新结核病,其中44.8%,22.9%和32.3%被诊断为新涂片阳性,涂片阴性并患有肺外结核(EPTB)登记了369例再治疗病例。与涂片阳性和涂片阴性的患者相比,EPTB患者的治愈率最高。涂片阳性失败中违约者的比例最高,其次是违约后涂片阳性,涂片阳性复发率最低。结论EPTB患者的治愈率较高,而肺结核患者的违约率更高。因此,由于未经治疗或未接受治疗的肺结核病例是导致社区疾病传播的原因,因此卫生和非卫生人员需要更高水平的动机。可以通过采取严格监督和监测等具体措施来降低违约率。 DOI:http://dx.doi.org/10.3126je.v5i1.12376

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