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首页> 外文期刊>Nepal Journal of Obstetrics and Gynaecology >Comparison of intramyometrial and intramuscular 15 methyl PGF2? against traditional prophylactic intramuscular methergin for the active management of third stage of labor
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Comparison of intramyometrial and intramuscular 15 methyl PGF2? against traditional prophylactic intramuscular methergin for the active management of third stage of labor

机译：肌内肌和肌内15甲基PGF2的比较？预防传统的预防性肌注麦角蛋白，积极管理第三产程

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Objective: To compare intramyometrial, intramuscular (I M) 15 methyl PGF 2α with IM Methergin on the duration and blood loss of 3rd and 4th stage of labor. Method : Prospective randomized control study, done from May 2004 to June 2005. Three hundred parturient women were randomly assigned to receive either an intramyometrial or IM 15 methyl PGF 2α or IM methergin immediately after delivery of baby. Duration of 3rd stage and blood loss during 3rd and 4th stage of labor was measured. Other parameters measured were – presence of atonic postpartum hemorrhage (PPH), need for MRP, and blood transfusion, any side effects of drugs. Results: Women who received prophylactic intramyometrial PGF 2α had significantly shorter duration of 3rd stage of labor (2.3 + 0.66 mins: p= 0.0000) compared to both IM group ( 3.04+1.03 mins) and IM methergin group ( 4.22+ 1.58 mins) and also significantly less blood loss ( median- 110ml; P= 0.0002) compare to both IM group (median-145ml) and IM methergin group( medin-197ml). Conclusion: Intramyometrial PGF 2α is better than IM PGF 2α and methergin in terms of reducing duration of 3rd stage and blood loss. Thus can be prophylactically used especially in those patients where even minimal blood loss will adversely affect the health of mother. DOI: http://dx.doi.org/10.3126jog.v3i2.10829 Nepal Journal of Obstetrics and Gynaecology Vol.3(2) 2008; 35-39
机译：目的：比较肌内，肌内（IM）15甲基PGF2α和IM Methergin对分娩第三，第四阶段的持续时间和失血量。方法：前瞻性随机对照研究，于2004年5月至2005年6月进行。300例分娩的妇女在分娩后立即被随机分配接受子宫内膜或IM 15甲基PGF2α或IM methergin。测量第三产程的持续时间和第三，第四产程的失血量。测得的其他参数包括–产后无瓣膜性出血（PPH），是否需要MRP，输血以及药物的任何副作用。结果：与IM组（3.04 + 1.03分钟）和IM methergin组（4.22+ 1.58分钟）相比，接受预防性子宫内膜内PGF2α的妇女的第三产程持续时间（2.3 + 0.66分钟：p = 0.0000）明显缩短。与IM组（中位数145ml）和IM methergin组（medin-197ml）相比，出血量也显着减少（中位数110ml; P = 0.0002）。结论：在减少第三阶段持续时间和失血方面，子宫内膜内PGF2α优于IM PGF2α和methergin。因此，可以预防性地使用它，尤其是在那些失血量最少会对母亲健康产生不利影响的患者中。 DOI：http://dx.doi.org/10.3126jog.v3i2.10829尼泊尔妇产科学杂志Vol.3（2）2008; 35-39岁

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