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首页> 外文期刊>Natural Product Radiance (NPR) >Protective effect of Solanum torvum on monosodium glutamate-induced neurotoxicity in mice
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Protective effect of Solanum torvum on monosodium glutamate-induced neurotoxicity in mice

机译：茄提取物对味精诱导的小鼠神经毒性的保护作用

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摘要

Solanum torvum is a well known traditional herbal medicinal plant used in many neurological disorders. The objective of the study was to evaluate the effects of S. torvum on monosodium glutamate (MSG) induced neurotoxicity. Swiss albino mice received MSG (1000 mg/kg, p.o) followed by a methanolic and hydroalcoholic extract of S. torvum (100 and 300 mg/kg, p.o) for 14 days. MSG-treated mice showed significant (p p S. torvum (100 and 300 mg/kg) showed normal behavior, significant (p p p S. torvum extracts reversed the histopathological changes induced by MSG. The study suggests that S. torvum seed extracts have the potential to ameliorate neuronal damage induced by MSG. Total flavonoid content of methanolic and hydroalcoholic extract of S. torvum was found to be 44±1.2 and 32±0.8 μg of rutin equivalent/mg of extracts and total phenolic content was found to be 70±0.28 and 52±0.62 μg of gallic acid equivalent/mg of extracts respectively.
机译：茄茄是用于许多神经系统疾病的众所周知的传统草药。该研究的目的是评估托氏链球菌对味精（MSG）诱导的神经毒性的影响。瑞士白化病小鼠接受味精（1000 mg / kg，p.o），然后接受曲霉链球菌的甲醇和水醇提取物（100和300 mg / kg，p.o），持续14天。经味精治疗的小鼠表现出显着（pp。S. torvum（100和300 mg / kg）表现出正常行为，显着（ppp。S. torvum提取物逆转了MSG诱导的组织病理学变化）。减轻味精诱导的神经元损伤。葡萄球菌甲醇和水醇提取物的总黄酮含量为44±1.2和芦丁当量/ mg提取物为32±0.8μg，总酚含量为70±0.28和52±0.62μg没食子酸当量/ mg提取物。

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