• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nepal Journal of Epidemiology >Breast Cancer and Dietary Fat Intake: A correlational study
【24h】

Breast Cancer and Dietary Fat Intake: A correlational study

机译：乳腺癌与膳食脂肪摄入量的相关性研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Breast cancer (BC) is reported to be the most common malignancies affecting women worldwide. There is a sharp increase in the BC incidence rate over the past three decades as previously low risk countries are moving towards high -calorie western diets. Few epidemiologic studies along with animal experiments have ascertained the role of dietary fat in developing BC. This study aimed to determine the correlation between per capita dietary fat consumption and incidence of BC. Methods: Three major data bases were used to conduct this correlational study. The data regarding consumption of fat and breast cancer incidence from 88 countries across five continents were extracted. The correlation coefficients between the incidence of BC and the fat consumption from the year 1990 to 2007 were calculated. Results : A statistically significant (P0.001) correlation between the average fat consumption and the crude BC incidence rate was observed and was more than 0.6, clearly indicating that there is a moderate to strong correlation with fat consumption and incidence of breast cancer (P0.001). Conclusions: Our observation indicated that increased total fat consumption increases the risk of developing BC. Consumption of dietary fat increases obesity thereby, increasing the risk of BC development. Dietary fat gets stored in the body since they undergo minimum oxidation as compared to carbohydrates and protein thereby, contributing to obesity a known risk factors for BC. Current study strengthens the evidence to support the hypothesis that non-genetic factors contribute to the occurrence of this disease.
机译：背景：据报道，乳腺癌（BC）是影响全世界女性的最常见恶性肿瘤。在过去的三十年中，由于以前的低风险国家正朝着高热量的西方饮食迈进，卑诗省的发病率急剧上升。很少有流行病学研究与动物实验一起确定饮食脂肪在发展BC中的作用。这项研究旨在确定人均饮食脂肪消耗与BC发病率之间的相关性。方法：使用三个主要数据库进行相关研究。提取了来自五大洲88个国家的脂肪摄入量和乳腺癌发病率数据。计算了1990年至2007年BC发病率与脂肪消耗之间的相关系数。结果：观察到平均脂肪消耗与BC粗脂肪发生率之间的统计显着性相关（P <0.001），且大于0.6，清楚地表明与脂肪消耗和乳腺癌的发生率之间存在中等至强相关性（P <0.001）。结论：我们的观察表明，增加总脂肪消耗会增加患BC的风险。食用脂肪会增加肥胖，从而增加BC患病的风险。饮食中的脂肪与碳水化合物和蛋白质相比，由于它们的氧化程度最低，因此会被储存在体内，从而导致肥胖，这是已知的BC危险因素。当前的研究加强了证据支持非遗传因素导致该病发生的假说。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号