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首页> 外文期刊>Kaohsiung Journal of Medical Sciences >Application of noninvasive brain stimulation for post-stroke dysphagia rehabilitation
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Application of noninvasive brain stimulation for post-stroke dysphagia rehabilitation

机译：无创性脑刺激在中风后吞咽困难康复中的应用

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摘要

Noninvasive brain stimulation (NIBS), commonly consisting of transcranial magnetic stimulation (TMS), transcranial direct-current stimulation (tDCS), as well as paired associative stimulation (PAS), has attracted increased interest and been applied experimentally in the treatment of post-stroke dysphagia (PSD). This review presented a synopsis of the current research for the application of NIBS on PSD. The intention here was to understand the current research progress and limitations in this field and to stimulate potential research questions not yet investigated for the application of NIBS on patients with PSD. Here we successively reviewed advances of repetitive TMS (rTMS), tDCS, and PAS techniques on both healthy participants and PSD patients in three aspects, including scientific researches about dysphagia mechanism, applied studies about stimulation parameters, and clinical trials about their therapeutic effects. The techniques of NIBS, especially rTMS, have been used by the researchers to explore the different mechanisms between swallowing recovery and extremity rehabilitation. The key findings included the important role of intact hemisphere reorganization for PSD recovery, and the use of NIBS on the contra-lesional side as a therapeutic potential for dysphagia rehabilitation. Though significant results were achieved in most studies by using NIBS on swallowing rehabilitation, it is still difficult to draw conclusions for the efficacy of these neurostimulation techniques, considering the great disparities between studies.
机译：通常由经颅磁刺激（TMS），经颅直流电刺激（tDCS）以及配对联想刺激（PAS）组成的非侵入性脑刺激（NIBS）引起了越来越多的兴趣，并已被实验性地用于治疗中风吞咽困难（PSD）。这篇综述介绍了有关NIBS在PSD上的应用的当前研究的概要。本文的目的是了解该领域当前的研究进展和局限性，并激发针对NIBS在PSD患者中的应用尚未调查的潜在研究问题。在这里，我们从三个方面回顾了健康受试者和PSD患者的重复TMS（rTMS），tDCS和PAS技术的进展，包括吞咽困难机理的科学研究，刺激参数的应用研究以及治疗效果的临床试验。研究人员已使用NIBS的技术，尤其是rTMS来探索吞咽恢复和肢体康复之间的不同机制。主要发现包括完整的半球重组对PSD恢复的重要作用，以及在对侧病变侧使用NIBS作为吞咽困难康复的治疗潜力。尽管在大多数研究中使用NIBS进行吞咽康复治疗均取得了显著成果，但考虑到研究之间的巨大差异，仍然难以就这些神经刺激技术的有效性得出结论。

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