...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>NeuroQuantology: an interdisciplinary journal of neuroscience and quantum physics >Lanthanum Zirconate Nanoparticles, used in Blades of Gas Turbine Engines, Can Disturb Behavior, Leukocyte Count and Antioxidant Metabolites of Vital Organs of Albino Mice
【24h】

Lanthanum Zirconate Nanoparticles, used in Blades of Gas Turbine Engines, Can Disturb Behavior, Leukocyte Count and Antioxidant Metabolites of Vital Organs of Albino Mice

机译：锆酸镧纳米粒子，用于燃气涡轮发动机叶片中，可干扰白化病小鼠重要器官的行为，白细胞计数和抗氧化代谢产物

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Lanthanum Zirconate (La2Zr2O7) nanoparticles (NPs) are generally used in blades of gas turbine engines to thermally insulate them and to protect them against hot and corrosive gas streams. The present research experiment was aimed to determine the effect of Lanthanum Zirconate NPs on selected aspects of behavior, serum biochemistry, complete blood count and antioxidant metabolites from vital organs of albino mice in a gender specific manner. Seven weeks old mice were administered orally with 25mg/ml solvent/Kg body weight of Lanthanum Zirconate nanoparticles for consecutive 22 days. Saline treated control groups were maintained in parallel. It was observed that neuromuscular coordination was significantly improved (P = 0.01) in NPs treated female mice while rearing frequency was significantly decreased (P = 0.004) in NPs treated male mice than their respective controls. Complete blood count analysis revelaed that NPs treated female mice had significantly reduced white blood cell (P = 0.04) and lymphocyte count (P = 0.02) than control group. It was observed that Superoxide dismutase concentrations in kidney (P = 0.04), Malonaldehyde concentrations in brain (P = 0.002), heart (P = 0.001), liver (P = 0.05) of male and in kidney (P = 0.001) of NPs treated female mice were significantly higher than their respective control groups. In conclusion, we are reporting that oral supplementation with 25mg/ml solvent/Kg body weight of Lanthanum Zirconate nanoparticles is affecting neuromuscular coordination, exploratory behavior, leukocyte count and antioxidant metabolites from vital organs in a gender specific manner with more pronounced effects in male.
机译：锆酸镧（La2Zr2O7）纳米颗粒（NPs）通常用于燃气涡轮发动机的叶片中，以使其隔热，并保护其免受高温和腐蚀性气流的侵害。本研究实验旨在确定性别特定方式下锆钛酸镧纳米粒对白化病小鼠重要器官的行为，血清生化，全血细胞计数和抗氧化代谢产物某些方面的影响。连续7天给7周龄的小鼠口服25 mg / ml溶剂/ Kg体重的锆酸镧纳米颗粒。盐水处理的对照组保持平行。观察到，与用NPs处理的雄性小鼠相比，用NPs处理的雌性小鼠的神经肌肉协调显着改善（P ＝ 0.01），而用NPs处理的雄性小鼠的饲养频率显着降低（P ＝ 0.004）。全血细胞计数分析表明，NPs治疗的雌性小鼠的白细胞（P = 0.04）和淋巴细胞计数（P = 0.02）明显低于对照组。观察到男性NPs在肾脏中的超氧化物歧化酶浓度（P = 0.04），脑中丙二醛的浓度（P = 0.002），心脏（P = 0.001），肝脏（P = 0.05）和肾脏（P = 0.001）治疗的雌性小鼠显着高于它们各自的对照组。总之，我们报告称，口服补充25mg / ml溶剂/千克体重的锆酸镧纳米颗粒正在以特定于性别的方式影响重要器官的神经肌肉协调，探索行为，白细胞计数和抗氧化代谢产物，对男性的影响更为明显。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号