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The reliability of neuroanatomy as a predictor of eloquence: a review

机译:神经解剖学作为口才预测指标的可靠性:综述

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The adjacency of intracranial pathology to canonical regions of eloquence has long been considered a significant source of potential morbidity in the neurosurgical care of patients. Yet, several reports exist of patients who undergo resection of gliomas or other intracranial pathology in eloquent regions without adverse effects. This raises the question of whether anatomical and intracranial location can or should be used as a means of estimating eloquence. In this review, the authors systematically evaluate the factors that are known to affect anatomical-functional relationships, including anatomical, functional, pathology-related, and modality-specific sources of variability. This review highlights the unpredictability of functional eloquence based on anatomical features alone and the fact that patients should not be considered ineligible for surgical intervention based on anatomical considerations alone. Rather, neurosurgeons need to take advantage of modern technology and mapping techniques to create individualized maps and management plans. An individualized approach allows one to expand the number of patients who are considered for and who potentially may benefit from surgical intervention. Perhaps most importantly, an individualized approach to mapping patients with brain tumors ensures that the risk of iatrogenic functional injury is minimized while maximizing the extent of resection.
机译:长期以来,颅内病理学与口才典范区域的邻接一直被认为是患者神经外科护理中潜在发病率的重要来源。然而,已有几篇报道说,在雄辩地区接受神经胶质瘤切除术或其他颅内病理检查的患者没有不良反应。这就提出了一个问题,即解剖位置和颅内位置是否可以或应该用作估计口才的手段。在这篇综述中,作者系统地评估了已知会影响解剖功能关系的因素,包括解剖学,功能,病理学相关和形态特定的变异性来源。这篇综述强调了仅基于解剖学特征的功能口才的不可预测性,以及仅基于解剖学的考虑因素不应认为患者不适合进行外科手术。相反,神经外科医生需要利用现代技术和制图技术来创建个性化的地图和管理计划。一种个性化的方法可以扩大考虑的患者数量,并可能从手术干预中受益。也许最重要的是,一种针对脑肿瘤患者的个体化方法可以确保在最大程度地切除范围的同时,将医源性功能性损伤的风险降到最低。

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