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首页> 外文期刊>Neurosurgical focus >Idiopathic intracranial hypertension following spinal deformity surgery in children
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Idiopathic intracranial hypertension following spinal deformity surgery in children

机译：小儿脊柱畸形手术后特发性颅内高压

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Idiopathic intracranial hypertension (IIH) after pediatric spinal deformity surgery has not been previously reported. The authors conducted a retrospective analysis of more than 1500 pediatric spinal surgeries performed between 1992 and 2011. From their analysis, they report on 3 adolescent patients who underwent uncomplicated segmental spinal instrumentation for pediatric spinal deformity correction and subsequently developed features of IIH. The common variables in these 3 patients were adolescent age, spinal deformity, being overweight, symptom onset within 2 weeks postoperatively, significant estimated blood loss, and intraoperative use of ε–aminocaproic acid (antifibrinolytic) injection. The authors postulate that the development of IIH could be the result of venous outflow obstruction due to derangement of the epidural venous plexus during surgery. The use of ε–aminocaproic acid could potentially have the risk of causing IIH, probably mediated through hyperfibrinogenemia, although there have not been published cases in the neurosurgical, orthopedic, cardiac, or general surgical literature. Idiopathic intracranial hypertension after spinal deformity correction is a condition that should be recognized by neurosurgeons and orthopedic surgeons, because appropriate intervention with early medical therapy can lead to a satisfactory clinical outcome.
机译：小儿脊柱畸形手术后的特发性颅内高压（IIH）尚未见报道。作者对1992年至2011年间进行的1500多次小儿脊柱外科手术进行了回顾性分析。从他们的分析中，他们报告了3例青少年患者，他们接受了不复杂的节段性脊柱器械矫正小儿脊柱畸形并随后发展了IIH的特征。这3例患者的共同变量是：青春期，脊柱畸形，超重，术后2周内出现症状，估计失血量明显以及术中使用ε-氨基己酸（抗纤溶蛋白）注射。作者推测IIH的发生可能是由于手术过程中硬膜外静脉丛的紊乱引起的静脉流出障碍。尽管在神经外科，整形外科，心脏或普通外科文献中尚未发表病例，但使用ε-氨基己酸可能有引起IIH的风险，可能是由高纤维蛋白原血症介导的。脊柱畸形矫正后的特发性颅内高压是神经外科医师和整形外科医师应认识到的疾病，因为早期药物治疗的适当干预可以导致令人满意的临床结果。

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