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Thermal injury to corticospinal tracts and postoperative motor deficits after laser interstitial thermal therapy

机译:激光间隙热疗后皮质脊髓束热损伤和术后运动功能障碍

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OBJECTIVE Laser interstitial thermal therapy (LITT) has been increasingly used to treat deep-seated tumors. Despite its being minimally invasive, there is a risk of LITT damaging adjacent critical structures, including corticospinal tracts (CSTs). In this study, the authors investigated the predictive value of overlap between the hyperthermic field and CSTs in determining postoperative motor deficit (PMDs). METHODS More than 140 patients underwent an LITT procedure in our institution between April 2011 and June 2015. Because of the tumor's proximity to critical structures, 80 of them underwent preoperative diffusion tensor imaging and were included in this study. Extent of the hyperthermic field was delineated by the software as thermal-damage-threshold (TDT) lines (yellow [43°C for 2 minutes], blue [43°C for 10 minutes], and white [43°C for 60 minutes]). The maximum volume and the surface area of overlaps between motor fibers and the TDT lines were calculated and compared with the PMDs. RESULTS High-grad...
机译:目的激光间质热疗法(LITT)已越来越多地用于治疗深部肿瘤。尽管LITT具有微创性,但仍有损坏邻近关键结构(包括皮质脊髓束(CST))的风险。在这项研究中,作者调查了高温场和CSTs重叠在确定术后运动障碍(PMD)中的预测价值。方法2011年4月至2015年6月间,我们机构对140例患者进行了LITT手术。由于肿瘤靠近关键结构,其中80例患者进行了术前弥散张量成像,并纳入了这项研究。该软件将高温场的范围定义为热损伤阈值(TDT)线(黄色[43°C 2分钟],蓝色[43°C 10分钟]和白色[43°C 60分钟] ])。计算了电机纤维和TDT线之间重叠的最大体积和表面积,并与PMD进行了比较。结果高等级...

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