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首页> 外文期刊>Nigerian Medical Journal >Prognostic risk factors for early diagnosing of Preeclampsia in Nulliparas
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Prognostic risk factors for early diagnosing of Preeclampsia in Nulliparas

机译：早期诊断子痫前期子痫的预后危险因素

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Background:Preeclampsia is of major complications of pregnancy that is associated with maternal morbidity and mortality. Therefore, prediction and early diagnosis of preeclampsia would be helpful for better controlling of related complications. Our study aimed to investigate risk factors helping to predict and early diagnose of preeclampsia.Materials and Methods:A total of 739 nulliparous women at their 24-28th weeks of the first pregnancy were enrolled in this multi-center cohort study. Incidence or absence of preeclampsia in this population was evaluated up to the end of pregnancy period. For each case, a record sheet was assigned that contained information about haematocrit level in weeks 24-28th of pregnancy, blood pressure, result of roll-over test in weeks 24-28th of pregnancy and the presence of disease up to end of the study. Diagnosis of preeclampsia was made based on gold standard.Results:Overall, 3.9 % of all cases developed preeclampsia. The mean maternal age, body mass index (BMI), years of education and positive roll-over test were significantly higher in preeclampsia group (P < 0.001). However, the mean gestational age and changes in the levels of haematocrit were significantly higher in normotensive cases (P < 0.001). Our combined model could predict preeclampsia with a sensitivity of 93% and a specificity of 80%.Conclusion:Simple combined model of demographic characteristics including maternal age, BMI, years of education and positive roll-over tests can predict preeclampsia without any cost for the patients.
机译：背景：先兆子痫是妊娠的主要并发症，与母亲的发病率和死亡率有关。因此，先兆子痫的预测和早期诊断将有助于更好地控制相关并发症。我们的研究旨在调查有助于预测先兆子痫的危险因素。材料与方法：这项多中心队列研究共纳入了739名初次怀孕的24岁至28周未生育妇女。评估直至妊娠期末的子痫前期发病率或无先兆子痫。对于每种情况，分配一个记录表，其中包含有关妊娠24-28周时的血细胞比容水平，血压，妊娠24-28周时的翻身测试结果以及直至研究结束的疾病存在情况的信息。结果：总的来说，所有病例中有3.9％发生了先兆子痫。子痫前期组的平均孕产妇年龄，体重指数（BMI），受教育年限和翻转试验阳性率显着更高（P <0.001）。然而，在正常血压的情况下，平均胎龄和血细胞比容水平的变化明显更高（P <0.001）。我们的组合模型可以预测先兆子痫，敏感性为93％，特异性为80％。结论：简单的人口特征（包括产妇年龄，BMI，受教育年限和阳性翻身试验）组合模型可以预测先兆子痫，而无需花费任何费用。耐心。

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