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首页> 外文期刊>Nigerian Journal of Physiological Sciences >Effects of Telfairia Occidentalis Seed Oil on Female Reproductive Functions in Wistar Rats
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Effects of Telfairia Occidentalis Seed Oil on Female Reproductive Functions in Wistar Rats

机译：西方仙人掌花籽油对Wistar大鼠雌性生殖功能的影响

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Summary: The effects of T. occidentalis seed oil on some female reproductive indices were investigated in Wistar rats. The study was divided into two phases: (estrous cycle and pregnancy). Animals were grouped into four: group A received distilled water (control), groups B, C and D received 400, 600 and 800 mg/kg bw of T. occidentalis seed oil respectively. The pattern of estrous cycle was determined for three weeks before and during the treatment. Thereafter, each group was sub- divided into two. The sub-group-1 rats were mated with male breeders, the litter size and birth weight of their offsprings was determined. Sub-group-2 rats were sacrificed and histology of organs and serum levels of LH, FSH and estrogen were assayed. There was no significant difference between the pre-treatment and post-treatment estrous cycle length. However, there was a significant decrease in the frequency of diestrus phase during treatment in all the experimental groups when compared with pre-treatment period (p & 0.05) but there was no significant difference in the diestrus phase when compared with the control group. Serum estrogen concentration was significantly reduced (p & 0.05) in the group that was treated with 800 mg/kg bw of T. occidentalis seed oil. Histology of the ovary and uterus in the experimental groups were similar to that of the control group. Birth weight of pups was significantly increased in the group treated with 600 mg/kg bw of T. occidentalis seed oil when compared with the control group (p & 0.05). The results of this study suggest that T. occidentalis seed oil does not alter estrous cycle in Wistar rats. Keywords: T. occidentalis , Wistar rats, Estrous cycle, diestrus, Estrogen.
机译：摘要：在Wistar大鼠中研究了西洋参种子油对某些女性生殖指数的影响。该研究分为两个阶段：（发情周期和妊娠）。将动物分为四组：A组接受蒸馏水（对照组），B，C和D组分别接受400、600和800 mg / kg bw的西方奇异果种子油。在治疗前和治疗中三周确定发情周期的模式。此后，将每个小组分为两部分。将第1亚组的大鼠与雄性饲养员交配，确定其后代的产仔数和出生体重。处死第二组的大鼠，测定器官的组织学，并测定LH，FSH和雌激素的血清水平。治疗前和治疗后发情周期长度之间没有显着差异。然而，与治疗前相比，在所有实验组中治疗期间二头肌阶段的频率显着降低（p ＜0.05），但是与对照组相比，二头肌阶段没有显着差异。在用800 mg / kg bw的西方奇异球菌种子油治疗的组中，血清雌激素浓度显着降低（p <0.05）。实验组卵巢和子宫的组织学与对照组相似。与对照组相比，在以600 mg / kg bw的西方西兰花种子油治疗的组中，幼崽的出生体重显着增加（p <0.05）。这项研究的结果表明，T。occidentalis种子油不会改变Wistar大鼠的发情周期。关键词：西洋参，Wistar大鼠，发情周期，二头肌，雌激素。

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