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首页> 外文期刊>Nigerian Journal of Physiological Sciences >Renal Doppler Indices in Children with Nephrotic Syndrome: Findings from a Tertiary Hospital in Nigeria
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Renal Doppler Indices in Children with Nephrotic Syndrome: Findings from a Tertiary Hospital in Nigeria

机译：肾病综合征患儿的肾脏多普勒指数：尼日利亚三级医院的发现

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Summary: The resistive and pulsatility indices are known tools for assessing renal function in kidney diseases, especially in proteinuric conditions like Paediatric Nephrotic syndrome (NS) which is a glomerular disease. However, there is a limited knowledge in the use of Doppler Resistive and pulsatility indices in the management of this disease condition. This was a case control study involving 53 cases and 57 controls. The Doppler parameters, resistive index (RI) and pulsatility index (PI) of the renal interlobar arteries were determined for the upper, middle, and lower poles bilaterally for both controls and cases. The mean RI on the right and left were 0.59 ± 0.06 and 0.58 ± 0.06 respectively for the NS cases whereas for the controls it was 0.61 ± 0.05 and 0.60 ± 0.04 on the right and left respectively. The mean PI on the right and left measured 0.96 ± 0.16 and 0.94 ± 0.15 respectively for the NS cases while that for the control cases measured 0.98 ± 0.13.and 0.95 ± 0.12 on the right and left respectively. Although, the interlobar arteries mean RIs were generally less than that for the controls, but only the left middle pole showed statistically significant mean difference (p= 0.004). There was also statistically significant mean difference (p= 0.048) between the cases and controls in the left middle pole PI. However, no correlation was found when the renal RI and PI are compared with the serum albumin and creatinine. Although there was no statistical significance between the mean RI and PI of the NS cases and controls, except in the left middle pole RI, it is recommended that Doppler ultrasound should still be part of management of Nephrotic syndrome patients especially those who have developed end stage renal disease in order to monitor their renal function. Keywords: Paediatric, Nephrotic Syndrome, Renal, Resistive Index, Pulsatility Index
机译：简介：电阻率和搏动性指数是用于评估肾脏疾病（尤其是蛋白尿病）（如肾小球疾病小儿肾病综合征）的肾功能的已知工具。然而，在该疾病状况的治疗中使用多普勒抵抗力和搏动指数的知识有限。这是一个病例对照研究，涉及53个病例和57个对照。确定对照和病例双侧上，中和下极的肾小叶间动脉的多普勒参数，电阻指数（RI）和搏动指数（PI）。 NS患者的平均RI分别为0.59±0.06和0.58±0.06，而对照组的RI则分别为0.61±0.05和0.60±0.04。 NS患者的平均PI分别为0.96±0.16和0.94±0.15，而对照组的PI则分别为0.98±0.13和0.95±0.12。虽然，叶间动脉的平均RIs通常小于对照组，但只有左中极显示出统计学上的显着性平均差异（p = 0.004）。左中极PI的病例与对照之间也存在统计学上的显着性均值差异（p = 0.048）。但是，将肾脏RI和PI与血清白蛋白和肌酐进行比较时，没有发现相关性。尽管NS患者和对照组的平均RI和PI之间无统计学意义，但左中极RI除外，建议多普勒超声仍应作为肾病综合征患者尤其是晚期肾病患者管理的一部分肾脏疾病，以监测其肾功能。关键词：儿科，肾病综合征，肾脏，抵抗指数，搏动指数

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