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Quality of life after different surgical procedures for the treatment of spinal metastases: results of a single-center prospective case series

机译:不同脊柱转移瘤手术方法后的生活质量:单中心前瞻性病例系列研究的结果

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OBJECTIVE The performance of surgery for spinal metastases is rapidly increasing. Different surgical procedures, ranging from stabilization alone to stabilization combined with corpectomy, are thereby performed for various indications. Little is known about the impact of these different procedures on patient quality of life (QOL), but this factor is crucial when discussing the various therapeutic options with patients and their families. Thus, the authors of this study investigated the effect of various surgical procedures for spinal metastases on patient QOL. METHODS The authors prospectively followed a cohort of 113 patients with spinal metastases who were referred to their clinic for surgical evaluation between July 2012 and July 2014. Quality of life was assessed using the EQ-5D at intake and at 3, 6, 9, and 12 months after treatment. RESULTS Nineteen patients were treated conservatively, 41 underwent decompressive surgery with or without stabilization, 47 underwent a piecemeal corpectomy procedure with stabilization and expandable cage reconstruction, and 6 had a stabilization procedure without decompression. Among all surgical patients, the mean EQ-5D score was significantly increased from 0.44 pretreatment to 0.59 at 3 months after treatment (p CONCLUSIONS Quality of life can improve significantly after various extensive and less extensive surgical procedures in patients with spinal metastases. The relatively invasive corpectomy procedure, as compared with alternative less invasive techniques, does not negatively affect outcome.
机译:目的脊柱转移的外科手术性能正在迅速提高。因此,针对各种适应症,执行了各种手术程序,范围从单纯稳定到结合体切除术的稳定。关于这些不同程序对患者生活质量(QOL)的影响知之甚少,但是在与患者及其家人讨论各种治疗选择时,这一因素至关重要。因此,本研究的作者调查了各种脊柱转移手术方法对患者生存质量的影响。方法作者前瞻性地追踪了队列的113例脊柱转移瘤患者,于2012年7月至2014年7月之间转诊至他们的诊所进行手术评估。生活质量在摄入时,3、6、9和10时使用EQ-5D进行评估。治疗后12个月。结果保守治疗19例,其中41例行减压行有或无稳定手术,47例行逐行全切除术,行稳定及可扩张的笼重建术,6例行稳定行无减压手术。在所有外科手术患者中,平均EQ-5D评分从治疗前的0.44明显提高到治疗后3个月的0.59(结论)。在各种广泛和较不广泛的脊柱转移瘤手术后,生活质量可以显着改善。与替代性微创技术相比,体切除术不会对预后产生负面影响。

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