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Validation of anthropometric and bioelectrical impedance analysis (BIA) equations to predict total body water in a group of Cameroonian preschool children using deuterium dilution method

机译:人体计量学和生物电阻抗分析(BIA)方程的验证,使用氘稀释法预测一组喀麦隆学龄前儿童的体内总水

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BackgroundLittle information is available on the validity of anthropometry or impedance-based equations for prediction of total body water (TBW) in African children. This study was designed to validate and develop equations to predict total body water in Cameroonian children. MethodsTBW was measured by deuterium dilution in 102 children between 24 and 60?months of age and compared with the ones predicted by 5 anthropometric and 7 BIA equations. Multiple linear regression analysis was used to develop prediction equations for TBW from anthropometric parameters. ResultsUnacceptable discrepancies in the estimates of TBW at individual level were noted with all the equations tested. The following new anthropometry and BIA equations for the estimation of TBW were respectively developed: TBW?=?6.488?+?0.434?×?sex???0.039?×?age?+?0.670?×?weight???0.081?×?MUAC (cm)???0.372?×?BMI (adjusted R 2?=?0.71, RMSE?=?3.6), and TBW?=??6.206?+?0.0037?×?height2/Z???0.041?×?age?+?0.265?×?weight?+?0.1214?×?height (adjusted R 2?=?0.68, RMSE?=?1.4). The cross-validation procedures revealed that the predicted values of TBW compared with measured values are accurate at a group level. ConclusionThe current published anthropometric and BIA equations are invalid for the estimation of TBW in Cameroonian preschool children. The newly developed anthropometry or BIA prediction equations are valid for use in Cameroonian children aged 24–60?months.
机译:背景很少有关于人体测量学或基于阻抗的方程式对非洲儿童体内总水(TBW)预测的有效性的信息。本研究旨在验证和开发方程以预测喀麦隆儿童的体内总水分。方法采用氘稀释法对102名24至60个月大的儿童中的TBW进行了测量,并将其与5个人体测量学和7个BIA方程所预测的相比较。多元线性回归分析用于从人体测量学参数建立TBW的预测方程。结果在所有测试方程中,个人水平的TBW估计值均出现不可接受的差异。分别开发了以下新的人体测量学和BIA方程,用于估算TBW:TBWα=α6.488α+α0.434α×性别=0.039α×年龄β+β0.​​670α×体重=0.081β。 ×·MUAC(cm)····························································································································································································································0.0037 ?height 2 / Z ??? 0.041?×?年龄?+?0.265?×?重量?+?0.1214?×?高度(调整后的R 2 ?=? 0.68,RMSE?=?1.4)。交叉验证程序显示,TBW的预测值与测量值相比在组级别上是准确的。结论当前公布的人体测量和BIA方程对于估计喀麦隆学龄前儿童的TBW无效。新开发的人体测量学或BIA预测方程式适用于24至60个月大的喀麦隆儿童。

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