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Radionuclide voiding pattern in children with unstable bladder

机译:不稳定膀胱患儿的放射性核素排尿方式

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BACKGROUND: The purpose of this study was to investigate bladder function parameters by means of quantitative radionuclide cystography (QRC) in anxious, irritable children with unstable bladder. METHODS: Quantitative radionuclide cystography was performed in 18 children aged between 8 and 12 years, without evidence of neurologic and nephrourologic disorders. Findings were compared with those obtained in 10 healthy children aged between 7 and 10 years. The dynamics of the bladder emptying were studied after intravenous injection of 37 MBq/10 kg b.w. 99mTc-diethylenetriaminepentaacetic acid (DTPA) in the posterior views. Images of 90 frames every 2 sec. were stored in the 64x64 computer matrix during voiding. The patients voided into a container and the volumes were measured. RESULTS: The parameters evaluated were: functional bladder capacity (ml) - FBC, expected bladder capacity (ml) - EBC, percentage of EBC (%), voided urine volume (ml) - VV, residual urine (ml) - RU, voiding time (sec) - VT, average flow rate (ml/sec) - AFR and peak flow rate (ml/sec) - PFR. There was a statistically significant difference between controls and children with unstable bladder in the following parameters: FBC 288 ± 33 vs. 244 ± 27 ml (p vs. 82 ± 6% (p vs. 202 ± 35 ml (p vs. 48 ± 19 ml (p vs. 9 ± 4 ml/sec. (p vs. 13 ± 3 ml/s (p CONCLUSION: The results show that quantitative radionuclide cystography is a simple, noninvasive method, which allows a good separation of patients with unstable bladder from the children with normal voiding pattern.
机译:背景:本研究的目的是通过定量放射性核素膀胱造影(QRC)研究焦虑,易怒的不稳定膀胱患儿的膀胱功能参数。方法:对18例8至12岁的儿童进行了放射性核素膀胱造影定量检查,没有神经系统疾病和肾脏疾病的证据。将调查结果与10名7至10岁健康儿童的调查结果进行了比较。在静脉内注射37 MBq / 10 kg b.w.之后研究膀胱排空的动力学。后视图为99mTc-二亚乙基三胺五乙酸(DTPA)。每2秒90张图像。在排空期间将其存储在64x64计算机矩阵中。将患者排入容器中并测量其体积。结果:评估的参数为:功能性膀胱容量(ml)-FBC,预期膀胱容量(ml)-EBC,EBC百分比(%),排尿量(ml)-VV,残余尿量(ml)-RU,排尿时间(秒)-VT,平均流速(ml / sec)-AFR和峰值流速(ml / sec)-PFR。在以下参数上,对照组和患有膀胱不稳定的儿童之间存在统计学上的显着差异:FBC 288±33 vs. 244±27 ml(p vs. 82±6%(p vs. 202±35 ml(p vs. 48± 19 ml(p vs. 9±4 ml / sec。(p vs. 13±3 ml / s(p vs. 13±3 ml / s(p vs. 13±3 ml / s))结论:结果表明,定量放射性核素膀胱造影是一种简单的无创方法,可以很好地分离出不稳定患者小儿膀胱有正常的排尿模式。

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