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首页> 外文期刊>Nuclear Medicine Review >SPECT brain perfusion findings in mild or moderate traumatic brain injury
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SPECT brain perfusion findings in mild or moderate traumatic brain injury

机译：在轻度或中度脑外伤中SPECT脑灌注的发现

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BACKGROUND: The purpose of this manuscript is to present the findings in the largest series of SPECT brain perfusion imaging reported to date for mild or moderate traumatic brain injury. ATIENTS AND METHODS: This is a retrospective evaluation of 228 SPECT brain perfusion-imaging studies of patients who suffered mild or moderate traumatic brain injury with or without loss of consciousness (LOC). All patients had no past medical history of previous brain trauma, neurological, or psychiatric diseases, HIV, alcohol or drug abuse. The patient population included 135 males and 93 females. The ages ranged from 11-88 years (mean 40.8). The most common complaints were characteristic of the postconcussion syndrome: headaches 139/228 (61%); dizziness 61/228 (27%); and memory problems 63/228 (28%). LOC status was reported to be positive in 121/228 (53%), negative in 41/228 (18%), and unknown for 63/228 (28%). [t?um.: = 225 a nie 228] RESULTS: Normal studies accounted for 52/228 (23%). For abnormal studies (176/228 or 77%) the findings were as follows: basal ganglia hypoperfusion 338 lesions (55.2%); frontal lobe hypoperfusion 146 (23.8%); temporal lobes hypoperfusion 80 (13%); parietal lobes hypoperfusion 20 (3.7%); insular and or occipital lobes hypoperfusion 28 (4.6%). Patients? symptoms correlated with the SPECT brain perfusion findings. The SPECT BPI studies in 122/228 (54%) were done early within 3 months of the date of the accident, and for the remainder, 106/228 (46%) over 3 months and less than 3 years from the date of the injury. In early imaging, 382 lesions were detected; in 92 patients (average 4.2 lesions per study) imaging after 3 months detected 230 lesions: in 84 patients (average 2.7 lesions per study). CONCLUSIONS: Basal ganglia hypoperfusion is the most common abnormality following mild or moderate traumatic brain injury (p = 0.006), and is more common in patients complaining of memory problem (p = 0.0005) and dizziness (p = 0.003). Early imaging can detect more lesions than delayed imaging (p = 0.0011). SPECT brain perfusion abnormalities can occur in the absence of LOC.
机译：背景：该手稿的目的是介绍迄今为止报道的针对轻度或中度外伤性脑损伤的最大系列SPECT脑灌注成像的发现。病人和方法：这是对228例SPECT脑灌注成像研究的回顾性评估，该研究对患有轻度或中度外伤性脑损伤而有无意识丧失（LOC）的患者进行了研究。所有患者均无以往脑外伤，神经或精神疾病，HIV，酒精或药物滥用的既往病史。患者人数包括135名男性和93名女性。年龄范围为11-88岁（平均40.8）。最常见的主诉是脑震荡后综合症的特征：头痛139/228（61％）;头晕61/228（27％）;和内存问题63/228（28％）。据报道，LOC状态为121/228（53％）为阳性，41/228（18％）为阴性，63/228（28％）未知。 [tum.：= 225 nie 228]结果：正常研究占52/228（23％）。对于异常研究（176/228或77％），发现如下：基底神经节灌注不足338个病变（55.2％）;额叶灌注不足146（23.8％）;颞叶灌注不足80（13％）;顶叶灌注不足20（3.7％）;岛叶和/或枕叶低灌注28（4.6％）。耐心？症状与SPECT脑灌注结果相关。在事故发生后的三个月内尽早在122/228（54％）中进行了SPECT BPI研究，对于其余的事故，在事故发生之日后的三个月内（不到3年）进行了106/228（46％）的BPI研究。受伤。在早期成像中，检测到382个病灶。 3个月后对92例患者（每个研究平均4.2个病灶）进行影像学检查，发现230个病灶：在84例患者中（每个研究平均2.7个病灶）。结论：基底神经节灌注不足是轻度或中度外伤性脑损伤后最常见的异常（p = 0.006），在抱怨记忆力障碍（p = 0.0005）和头晕（p = 0.003）的患者中更常见。与延迟成像相比，早期成像可以检测到更多的病变（p = 0.0011）。没有LOC时会发生SPECT脑灌注异常。

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