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首页> 外文期刊>Nuclear Medicine Review >Assessment of clinical usefulness of parametric clearance images in diagnosis of kidney cicatrisation in children with chronic infections of the urinary tract
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Assessment of clinical usefulness of parametric clearance images in diagnosis of kidney cicatrisation in children with chronic infections of the urinary tract

机译：评估参数清除图像在诊断患有尿路慢性感染的儿童肾脏瘢痕形成中的临床实用性

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BACKGROUND : Cicatrisation of the renal cortex is closely related to chronic infections of the urinary system. Static renal scintigraphy is used as the method enabling detection of local defects of radiopharmaceutical uptake, and is treated as the “gold standard” in the diagnosis of renal scars. The aim of the reported investigation was a comparison of the diagnostic efficacy of parametric clearance images and the conventional summation images — obtained from dynamic scintigraphy — in the detection of local defects of renal function. As the “gold standard” for the above comparison, the static scintigraphy of kidneys was accepted. MATERIAL AND METHODS : Forty-one patients (age 4–19 years), 28 girls and 13 boys, participated in the study. Altogether, 73 kidneys were analyzed (in 9 patients, only one kidney). In each patient dynamic renal scintigraphy was performed after IV administration of 99mTc EC (ethylenedicysteine) and static planar renal scintigraphy using 99mTc-DMSA (dimercaptosuccinic acid) as a reference method. From the dynamic study, summation and parametric clearance images were generated. Each kidney was divided into 3 segments (upper, middle, lower); altogether 219 segments were evaluated by modified Howard’s scale. Planar and oblique projection images were compared with corresponding summation and parametric clearance images. RESULTS AND CONCLUSIONS : Parametric clearance imaging has a higher sensitivity and accuracy for detection of regional post-inflammatory changes in the kidneys than conventional summation images (p Nuclear Med Rev 2010; 13, 1: 8–14
机译：背景：肾皮质的ica骨化与泌尿系统慢性感染密切相关。静态肾闪烁显像术被用作检测放射性药物摄取局部缺陷的方法，并被视为诊断肾疤痕的“金标准”。报道的研究的目的是比较参数清除图像和常规总和图像（从动态闪烁扫描获得的图像）在检测肾功能局部缺陷方面的诊断功效。作为上述比较的“金标准”，接受了肾脏的静态闪烁显像。材料与方法：41名患者（4-19岁），28名女孩和13名男孩参加了研究。总共分析了73个肾脏（在9例患者中，只有1个肾脏）。在每位患者中，静脉内注射99mTc EC（乙烯半胱氨酸）后进行动态肾脏闪烁显像，并使用99mTc-DMSA（二巯基琥珀酸）作为参考方法进行静态平面肾脏闪烁显像。从动态研究中，得出了总和和参数间隙图像。每个肾脏分为3个部分（上，中，下）。修改后的霍华德量表总共评估了219个细分受众群。将平面和倾斜投影图像与相应的求和和参数间隙图像进行比较。结果与结论：与传统的总和图像相比，参数清除成像对检测肾脏局部炎症后变化具有更高的灵敏度和准确性（p Nuclear Med Rev 2010; 13，1：8–14

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