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Health-related quality of life of chronic obstructive pulmonary disease patients: Results from a community based cross-sectional study in Aligarh, Uttar Pradesh, India

机译:慢性阻塞性肺疾病患者的与健康有关的生活质量:来自印度北方邦阿里加尔的社区横断面研究结果

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Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. It is an incurable disease with improvement in quality of life (QOL) as a major focus area for management. This study assesses the QOL of COPD patients and the factors affecting it. Materials and Methods: All 124 patients diagnosed with COPD in a larger cross-sectional study to determine the prevalence of COPD were assessed for their QOL using St. George's respiratory questionnaire for COPD patients (SGRQ-C). Spirometry was performed to assess lung function and diagnose COPD. Chronic lung disease (CLD) severity index was used to assess the severity of symptoms and the Medical Research Council questionnaire was used to assess the severity of dyspnea. Sociodemographic data regarding the patients were also recorded. Results: Patients with COPD showed significantly reduced health-related quality of life (HRQOL). CLD estimate for severity of lung disease and the Medical Research Council assessment for dyspnea and the duration of illness showed a highly significant positive correlation with HRQOL. There was a statistically significant negative correlation between lung function and SGRQ-C score. Increasing age, increased quantum of smoking, and lower socioeconomic status were correlated with poorer HRQOL. No association between QOL and education, body mass index (BMI), and gender was observed. Conclusion: This study showed that Indian patients with COPD had reduced HRQOL. Poor lung function, increased disease duration and smoking, and worsening symptoms impacted HRQOL negatively.
机译:背景:慢性阻塞性肺疾病(COPD)的特点是气流受限,不能完全逆转。它是一种不治之症,其生活质量(QOL)有所提高,是管理的主要重点领域。这项研究评估了COPD患者的生活质量及其影响因素。材料和方法:使用圣乔治针对COPD患者的呼吸调查问卷(SGRQ-C),在一项较大的横断面研究中确定所有COPD患病率的124名患者,以确定其COOL的方式评估其生活质量。进行肺活量测定以评估肺功能并诊断COPD。慢性肺病(CLD)严重程度指数用于评估症状的严重程度,而医学研究委员会调查表用于评估呼吸困难的严重程度。还记录了有关患者的社会人口统计学数据。结果:COPD患者的健康相关生活质量(HRQOL)大大降低。 CLD对肺部疾病严重程度的估计以及医学研究理事会对呼吸困难和疾病持续时间的评估显示与HRQOL高度显着正相关。肺功能与SGRQ-C评分之间存在统计学上的显着负相关。年龄增加,吸烟量增加以及社会经济地位降低与HRQOL差有关。生活质量与教育程度,体重指数(BMI)和性别之间没有关联。结论:该研究表明印度COPD患者HRQOL降低。肺功能差,疾病持续时间增加和吸烟以及症状恶化对HRQOL产生负面影响。

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