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Plant peroxisomes: A nitro-oxidative cocktail

机译：植物过氧化物酶体：硝基氧化混合物

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Although peroxisomes are very simple organelles, research on different species has provided us with an understanding of their importance in terms of cell viability. In addition to the significant role played by plant peroxisomes in the metabolism of reactive oxygen species (ROS), data gathered over the last two decades show that these organelles are an endogenous source of nitric oxide (NO) and related molecules called reactive nitrogen species (RNS). Molecules such as NO and H2O2 act as retrograde signals among the different cellular compartments, thus facilitating integral cellular adaptation to physiological and environmental changes. However, under nitro-oxidative conditions, part of this network can be overloaded, possibly leading to cellular damage and even cell death. This review aims to update our knowledge of the ROS/RNS metabolism, whose important role in plant peroxisomes is still underestimated. However, this pioneering approach, in which key elements such as β-oxidation, superoxide dismutase (SOD) and NO have been mainly described in relation to plant peroxisomes, could also be used to explore peroxisomes from other organisms.
机译：尽管过氧化物酶体是非常简单的细胞器，但对不同物种的研究使我们了解了它们在细胞生存力方面的重要性。除了植物过氧化物酶体在活性氧（ROS）的代谢中发挥重要作用外，近二十年来收集的数据还表明这些细胞器是一氧化氮（NO）和相关分子的内源性来源，称为活性氮（ RNS）。 NO和H 2 O 2 等分子在不同的细胞区室中充当逆行信号，从而促进细胞整体适应生理和环境变化。然而，在硝基氧化条件下，该网络的一部分可能过载，可能导致细胞损伤甚至细胞死亡。这篇综述旨在更新我们对ROS / RNS代谢的了解，而ROS / RNS在植物过氧化物酶体中的重要作用仍被低估了。但是，这种开创性的方法也可以用于探索其他生物体的过氧化物酶体，其中主要针对植物过氧化物酶体描述了诸如β-氧化，超氧化物歧化酶（SOD）和NO等关键元素。

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