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首页> 外文期刊>Radiologia Brasileira >Microcalcifica??es amorfas suspeitas detectadas na mamografia digital: correla??o histológica
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Microcalcifica??es amorfas suspeitas detectadas na mamografia digital: correla??o histológica

机译：在数字乳腺X射线摄影术上发现的疑似非晶微钙化：组织学相关性

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Objective: To evaluate suspicious amorphous calcifications diagnosed on full-field digital mammography (FFDM) and establish correlations with histopathology findings. Materials and Methods: This was a retrospective study of 78 suspicious amorphous calcifications (all classified as BI-RADS ? 4) detected on FFDM. Vacuum-assisted breast biopsy (VABB) was performed. The histopathological classification of VABB core samples was as follows: pB2 (benign); pB3 (uncertain malignant potential); pB4 (suspicion of malignancy); and pB5 (malignant). Treatment was recommended for pB5 lesions. To rule out malignancy, surgical excision was recommended for pB3 and pB4 lesions. Patients not submitted to surgery were followed for at least 6 months. Results: Among the 78 amorphous calcifications evaluated, the histopathological analysis indicated that 8 (10.3%) were malignant/suspicious (6 classified as pB5 and 2 classified as pB4) and 36 (46.2%) were benign (classified as pB2). The remaining 34 lesions (43.6%) were classified as pB3: 33.3% were precursor lesions (atypical ductal hyperplasia, lobular neoplasia, or flat epithelial atypia) and 10.3% were high-risk lesions. For the pB3 lesions, the underestimation rate was zero. Conclusion: The diagnosis of precursor lesions (excluding atypical ductal hyperplasia, which can be pB4 depending on the severity and extent of the lesion) should not necessarily be considered indicative of underestimation of malignancy. Suspicious amorphous calcifications correlated more often with precursor lesions than with malignant lesions, at a ratio of 3:1.
机译：目的：评估在全视野乳腺X线摄影术（FFDM）上诊断出的可疑无定形钙化，并与组织病理学发现建立关联。材料和方法：这是一项对在FFDM上检测到的78个可疑无定形钙化（均归类为BI-RADS？4）的回顾性研究。进行了真空辅助的乳房活检（VABB）。 VABB核心样品的组织病理学分类如下：pB2（良性）; pB3（不确定的恶性潜能）; pB4（怀疑恶性肿瘤）;和pB5（恶性）。建议对pB5病变进行治疗。为了排除恶性肿瘤，建议手术切除pB3和pB4病变。未接受手术的患者至少随访6个月。结果：在评估的78个无定形钙化中，组织病理学分析显示，有8个（10.3％）为恶性/可疑（6个分类为pB5，2个分类为pB4）和36个（46.2％）为良性（分类为pB2）。其余的34个病变（43.6％）被分类为pB3：33.3％为前体病变（非典型导管增生，小叶赘生或扁平上皮非典型性增生），10.3％为高危病变。对于pB3病变，低估率为零。结论：诊断为前体病变（不典型导管增生除外，根据病变的严重程度和程度可以为pB4）不一定被认为是低估了恶性肿瘤的指标。可疑的无定形钙化与前体病变的相关性高于与恶性病变的相关性，比率为3：1。

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