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首页> 外文期刊>Research Journal of Medical Sciences >Pattern of Neurological Disorders among HIV Seropositive Adult Nigerians with Psychiatric Moridity
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Pattern of Neurological Disorders among HIV Seropositive Adult Nigerians with Psychiatric Moridity

机译：HIV阳性的尼日利亚患有精神病的成年人的神经系统疾病的模式

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The neurological complications of HIV infection are still an unresolved problem and contribute importantly to patient morbidity and mortality. Myriads of neurological conditions can complicate HIV/AIDS. These include directly HIV-associated complications, opportunistic infections and neoplasms. Neurological complications can also be provoked by so called immune reconstitution phenomena. Overall, secondary disease of the CNS occurs in approximately one-third of patients with AIDS. Neurological conditions could coexist with psychiatric illnesses especially in a setting of immunosuppression as seen in HIV/AIDS. This study aims to determine the pattern of neurological comorbidity among HIV seropositive psychiatric patients in a tertiary centre in Nigeria and hence contribute to the existing (albeit scanty) knowledge base of NeuroAIDS in Africa. All patients presenting at the neuropsychiatry Out-patient Clinics and the Accident and Emergency department of the University of Port Harcourt Teaching hospital between January 2003 and December 2005 were studied prospectively for neurological comorbidity and screened for HIV infection. One thousand six hundred and eleven psychiatric patients were seen and tested for HIV seropositivity over the study period. 61(3.8%) were found to be positive for HIV I and/or II. 31 (50.8%) had no neurological deficit, 29(46.0%) had acute/subacute encephalitis, 13 (21.3%) had peripheral neuropathies, 7 (11.5%) each had Cranial nerve palsies (I, V, VII), dysarthria /aphasia, AIDS dementia complex and epilepsy, 6 (9.8%) each had diffuse headache, meningism and amnestic syndrome, 4 (6.8%) had hemiparesis/hemiplegia, while 3 (4.9%) each had severe hemicranial headache and myopathy. There is a high incidence of neurological comorbidity among psychiatric patients with HIV infection. Mental health practitioners need to be alert to this possibility especially where life threatening conditions exist. In most African countries, economic and medical resources are less than adequate to deal with a problem of this magnitude.
机译：HIV感染的神经系统并发症仍未解决，对患者的发病率和死亡率起重要作用。无数的神经系统疾病会使艾滋病毒/艾滋病复杂化。这些包括直接与HIV相关的并发症，机会性感染和肿瘤。所谓的免疫重建现象也可能引起神经系统并发症。总体而言，中枢神经系统继发性疾病约占艾滋病患者的三分之一。神经系统疾病可能与精神疾病共存，尤其是在艾滋病毒/艾滋病所致的免疫抑制情况下。这项研究的目的是确定尼日利亚三级中心的HIV血清反应阳性精神病患者的神经系统合并症的模式，从而为非洲NeuroAIDS的现有知识库（尽管不足）做出贡献。对2003年1月至2005年12月在神经精神科门诊诊所和哈科特港大学教学医院急诊室就诊的所有患者进行了前瞻性研究，以了解神经系统合并症并筛查HIV感染情况。在研究期间，共对1,161名精神病患者进行了检查并测试了HIV血清阳性。发现61（3.8％）的HIV I和/或II阳性。 31例（50.8％）无神经功能缺损，29例（46.0％）患有急性/亚急性脑炎，13例（21.3％）患有周围神经病，7例（11.5％）均患有颅神经麻痹（I，V，VII），构音障碍/失语症，艾滋病痴呆综合症和癫痫病，分别有6例（9.8％）患有弥漫性头痛，脑膜炎和遗忘综合症，4例（6.8％）患有偏瘫/偏瘫，而3例（4.9％）则患有严重的偏头痛和肌病。 HIV感染的精神病患者中神经系统合并症的发生率很高。心理保健从业者需要对这种可能性保持警惕，尤其是在存在威胁生命的情况下。在大多数非洲国家中，经济和医疗资源不足以解决如此严重的问题。

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