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首页> 外文期刊>Revista de la Sociedad Espanola del Dolor >La formulación magistral en la escalera analgésica de la OMS como estrategia de la atención farmacéutica
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La formulación magistral en la escalera analgésica de la OMS como estrategia de la atención farmacéutica

机译：WHO镇痛阶梯中的药物配方作为药物治疗策略

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摘要

A magistral formulation (MF) is a drug prepared for a given patient by the pharmacist or under his/her supervision, specifically according to a detailed medical prescription of the medicinal substances that it contains and applying the technical and scientific standards of the pharmaceutical art, that is dispensed by the pharmacist providing the patient with adequate information. This is an possible cost-effective strategy that can fill in a safe and effective way some of the therapeutic gaps or deficiencies that are found in the analgesic arsenal available in the market. The participation of the hospital pharmacist in the MF is regulated by law in terms of manufacturing and production, but the integration of this professional in the clinical team that provides care to patients facilitates the identification of therapeutic deficiencies that can be overcame by the MF. In this paper we describe the preparations, elaborated as MF and classified according to their route of administration, that are provided by the assistant hospital pharmacist of the Pain Unit at the General University Hospital Trust of Valencia, as well as their position within the WHO analgesic scale. Morphine preparations in drop, syrup or lidocain gel are prepared for their oral administration; solutions of acetic acid, dexametasone and lidocaine with different strengths are prepared for their transdermal administration; morphine and capsaicine plus ketamine gels are prepared for their topical administration, as well as injectable preparations for their intraarticular or intraspinal administration.
机译：岩浆制剂（MF）是由药剂师或在其监督下为特定患者制备的药物，特别是根据其所含药物的详细医学处方并应用制药领域的技术和科学标准，药剂师可为患者提供足够的信息。这是一种可能的具有成本效益的策略，可以安全有效地填补市场上可用的止痛药库中存在的某些治疗空白或缺陷。医院药剂师在MF中的参与受制造和生产方面的法律约束，但是该专业人员在为患者提供护理的临床团队中的整合有助于发现MF可以克服的治疗缺陷。在本文中，我们描述了由瓦伦西亚综合大学医院信托基金会疼痛科助理医院药剂师提供的制剂，按MF进行分类并根据给药途径进行分类，以及它们在世界卫生组织镇痛药中的地位规模。滴剂，糖浆剂或利多卡因凝胶中的吗啡制剂可以口服。制备不同强度的醋酸，地塞米松和利多卡因溶液进行透皮给药;吗啡和辣椒素加上氯胺酮凝胶可进行局部给药，也可进行关节内或脊柱内给药。

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