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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Prevalence of hemophilia in six cuban provinces
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Prevalence of hemophilia in six cuban provinces

机译：六个古巴省的血友病患病率

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Introduction: hemophilia is an inherited bleeding disorder; its incidence is almost constant in different populations. Since the 80thdecade a multidisciplinary group for the care of patients with hemophilia was created at the Instituto de Hematología e Inmunología. Nowadays a national comprehensive care program allows patients to receive a continuous monitoring and an effective treatment. Objective: to know prevalence of patients with hemophilia in Cuba. Results: data of 229 patients from 5 provinces and the special municipality Isla de la Juventud were included, which covered 58,71% of the total patients registered in Cuba. The information included demographic data, severity of hemophilia, presence of inhibitors and infection status for viral diseases. Hemophilia A patients were 188 (82.10%) and 41 (17.90%) with hemophilia B. The disease was severe in 56.33 % of patients, moderate in 24 %, and mild in 19.70 %. Inhibitors were present in 17.03 % of the patients. Human immunodeficiency virus infection was present only in 0.87 % of patients and hepatitis C virus infection in 39.03 %. The mean age at diagnosis was 2.15 years. Conclusions: the general age-adjusted prevalence was 9.63 cases of hemophilia per 100 000 male and the main prevalence of patients was found in ages between 20 and 59 years.
机译：简介：血友病是一种遗传性出血性疾病;在不同人群中其发病率几乎是恒定的。自80年代以来，血液病和免疫研究所成立了一个多学科的血友病患者护理小组。如今，一项国家综合护理计划允许患者接受持续的监测和有效的治疗。目的：了解古巴血友病患者的患病率。结果：包括来自5个省和尤文图斯市的229名患者的数据，涵盖了在古巴登记的总患者的58.71％。这些信息包括人口统计数据，血友病的严重程度，抑制剂的存在以及病毒性疾病的感染状况。 A型血友病患者分别为188例（82.10％）和41例（17.90％）患有B型血友病。该病的严重程度为56.33％，中度为24％，轻度为19.70％。 17.03％的患者中存在抑制剂。人类免疫缺陷病毒感染仅占0.87％，丙型肝炎病毒感染占39.03％。诊断时的平均年龄为2.15岁。结论：经年龄调整的普遍患病率为每100 000男性中有9.63例血友病，并且该患者的主要患病率在20至59岁之间。

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