首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Sobrecarga de hierro: complicaci?3n frecuente del trasplante de progenitores hematopoy??ticos
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Sobrecarga de hierro: complicaci?3n frecuente del trasplante de progenitores hematopoy??ticos

机译:铁超负荷:造血干细胞移植的常见并发症

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Iron overload is common in hematopietic stem cell transplantation (HSCT) recipients. In these patients, pre- and early post-transplant ferritin and transferrin saturation were found to be highly elevated due to high transfusion requirements. In addition to that, post-HSCT iron overload may be related to other complications such as infections, mucositis, and acute graft-versus-host disease. An elevated ferritin level before allogeneic HSCT is an adverse prognostic factor for overall and nonrelapse mortality. There are several diagnostic tools for iron overload but ferritinis still one of the most used.
机译:铁超载在造血干细胞移植(HSCT)受者中很常见。在这些患者中,由于较高的输血要求,发现移植前和移植后早期铁蛋白和转铁蛋白的饱和度高度升高。除此之外,HSCT后铁超负荷可能与其他并发症有关,例如感染,粘膜炎和急性移植物抗宿主病。异基因HSCT之前铁蛋白水平升高是总体和非复发死亡率的不利预后因素。有几种用于铁过载的诊断工具,但铁蛋白仍然是最常用的诊断工具之一。

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