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首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Study of the central nervous system in patients with drepanocytic anemia
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Study of the central nervous system in patients with drepanocytic anemia

机译：七叶性贫血患者中枢神经系统的研究

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摘要

35 adult patients with drepanocytic anemia were studied. They were divided into 2 groups: group 1 was composed of 24 patients without history of central nervous system crisis (15 males and 9 females), whereas group 2 included 11 cases with crisis history (6 males and 5 females). Average age was 31 years old for males and 29 for females. All the patients were under basal conditions. The time elapsed between the crisis and the study was 4.7 years. No significant differences were observed between the hemoglobin figures and the reticulocytes of both groups. A marked increase of the brain blood velocity was found in all the patients from group 1 and group 2 (p 0.05 y p 0.001, respectively). In 13 patients from group 1 (54.1 %) the brain blood flow presented modifications, whereas it was altered in all patients from group 2. In 13 cases from group 1 (76.4 %) the electroencephalogram was normal, but it was altered in 87.5 % of the patients from group 2. In 4 patients from group 1 (23.5 %), the brain electrical activity showed some modification. Computerized axial tomography was normal in 19 patients from group 1. Some alteration was detected in 3 cases from group 2 (37.5 %).
机译：研究了35名成人的右脑贫血患者。他们分为2组：第1组由24例无中枢神经系统疾病史的患者组成（男性15例，女性9例），而第2组包括11例具有历史病史的患者（男性6例，女性5例）。男性平均年龄为31岁，女性为29岁。所有患者均处于基础状态。从危机到研究之间的时间是4.7年。两组的血红蛋白值和网织红细胞之间均未观察到显着差异。在第1组和第2组的所有患者中均发现脑血流速度明显升高（分别为p <0.05 y p <0.001）。第1组的13例患者（54.1％）的脑血流出现了变化，而第2组的所有患者的脑血流均发生了改变。第1组的13例（76.4％）的脑电图正常，但其脑电图却改变了87.5％组2的患者中有1例患病。在第1组的4例患者中（23.5％），脑电活动表现出一定程度的改变。第一组的19例患者的计算机轴向断层扫描正常，第二组的3例（37.5％）出现了改变。

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