...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Rasayan Journal of Chemistry >ELECTROCATALYTIC OXIDATION OF TRYPTOPHAN AND TYROSINE USING DENSELY PACKED COBALT OXIDE SANDWICHED GRAPHENE STACKS MODIFIED ELECTRODE
【24h】

ELECTROCATALYTIC OXIDATION OF TRYPTOPHAN AND TYROSINE USING DENSELY PACKED COBALT OXIDE SANDWICHED GRAPHENE STACKS MODIFIED ELECTRODE

机译：稠密袋装氧化钴夹心石墨烯叠层修饰电极对三苯胺和酪氨酸的电催化氧化

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Herein, we construct a novel non-enzymatic, simple, selective and sensitive determination of Tryptophan and Tyrosine sensor. Cobalt oxide sandwiched graphene nanocomposite (COSG-NC) was successively synthesized through self-assembly method and immobilized on the surface of the wax impregnated graphite electrode via a simple drop and dry method. Surface topography of the densely packed COSG-NC electrode was confirmed by atomic force microscope analysis. The fabricated modified electrode showed an exceptional electrocatalytic response for Trp and Tyr oxidation occurred at a reduced overvoltage. Under optimal experimental conditions, the COSG-NC modified electrode demonstrated the extensive determination range from 24 × 10~(-6) M to 1 × 10~(-3) M and 41 × 10~(-6) M to 1 × 10~(-6) M with low limit of detection in the range of 8.2 × 10~(-6) M and 13 × 10~(-6) M (S/N = 3) of Trp and Tyr, respectively. The superior responses of the modified electrode for Trp and Tyr have mainly ascribed to the nanocomposites having large surface area with more electroactive sites of Co_3O_4 and synergistic effect of graphene nanocomposites. This work offered a reasonable approach for future research in enzyme-free amperometric sensors for biomolecules determination.
机译：本文中，我们构建了色氨酸和酪氨酸传感器的新型非酶，简单，选择性和灵敏测定方法。通过自组装法连续合成了氧化钴夹心石墨烯纳米复合材料（COSG-NC），并通过简单的滴加干燥法将其固定在蜡浸石墨电极的表面。通过原子力显微镜分析确认了紧密堆积的COSG-NC电极的表面形貌。制成的修饰电极对Trp表现出出色的电催化响应，并且在降低的过电压下发生Tyr氧化。在最佳实验条件下，COSG-NC修饰电极的测定范围从24×10〜（-6）M到1×10〜（-3）M和41×10〜（-6）M到1×10 〜（-6）M的检测下限分别在Trp和Tyr的8.2×10〜（-6）M和13×10〜（-6）M（S / N = 3）范围内。修饰电极对Trp和Tyr的优异响应主要归因于具有较大表面积且具有更多Co_3O_4的电活性位和纳米石墨烯纳米复合材料的协同作用的纳米复合材料。这项工作为未来用于生物分子测定的无酶安培传感器的研究提供了合理的方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号