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Effect of an E2 vaccine candidate of classical swine fever on bioproductive indicators at a pig farm

机译:猪瘟E2候选疫苗对养猪场生物生产指标的影响

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Classical swine fever (CSF) belongs to the group of diseases classified as notifiable to the World Organization for Animal Health (OIE). Prophylactic and systematic vaccination with modified live virus has been the main strategy for controlling CSF in large endemic areas, although, to meet their limitations, the so-called «marker vaccines» have been developed. In Cuba, a new vaccine candidate against CSF virus has been developed based on the E2 glycoprotein of its viral envelope (CVE2). After passing successfully through a series of laboratory tests, its evaluation under field conditions was required; as part of the various experiments carried out, it was decided to evaluate the behavior of the bioproductive indicators at a farm before and after the application of CVE2. The studies were conducted at a pig farm with a history of CSF endemism for several years where the animals were regularly vaccinated with the lapinized Chinese strain vaccine (LABIOFAM S.A.) as part of the control of the disease and the CVE2 began to be applied. After the CVE2 application, improvement of the bioproductive indicators was observed in the population studied.
机译:古典猪瘟(CSF)属于被分类为世界动物卫生组织(OIE)应通报的疾病。尽管为了满足其局限性,已经开发了所谓的“标志疫苗”,但对改性活病毒进行预防性和系统性疫苗接种已成为控制大流行地区脑脊液的主要策略。在古巴,已经基于其病毒包膜的E2糖蛋白(CVE2)开发了一种针对CSF病毒的新型候选疫苗。成功通过一系列实验室测试后,需要在现场条件下进行评估;作为进行的各种实验的一部分,决定评估在施用CVE2前后农场中生物生产指标的行为。该研究在具有CSF流行病史的养猪场进行了数年,在该猪场中定期给他们接种中国化的犬瘟疫苗(LABIOFAM S.A.)作为控制该疾病的一部分,并开始应用CVE2。施用CVE2后,在研究人群中观察到生物生产指标的提高。

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