LIPOSOMES BEHAVIOR IN ANTIBIOTICS AND RADIOFREQUENCY FIELD ENVIRONMENT

MARIA-MINODORA IORDACHE; MIHAELA-GEORGETA MOISESCU; EUGENIA KOVáCS; T. SAVOPOL

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LIPOSOMES BEHAVIOR IN ANTIBIOTICS AND RADIOFREQUENCY FIELD ENVIRONMENT

机译：脂质体在抗生素和放射频率场环境中的行为

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Liposomes are largely used today as drug carriers. Their behavior in various chemical and physical environments should be well known in view of a rational design of vesicles of appropriate formulations. We investigated the liposomal membrane behavior under different physical and chemical conditions such as exposure to antibiotics, radiofrequecy fields and thermal changes. Measuring the Generalized Polarization of laurdan-labeled liposomes in the presence of the charged aminoglycoside gentamicin, under exposure to 2.45 GHz and under cyclic variation of temperature, the phase transition behavior of the phospholipids was characterized.

机译：脂质体如今被广泛用作药物载体。考虑到适当制剂的囊泡的合理设计，它们在各种化学和物理环境中的行为应该是众所周知的。我们研究了在不同物理和化学条件下的脂质体膜行为，例如暴露于抗生素，射频场和热变化。在带电的氨基糖苷庆大霉素的存在下，在暴露于2.45 GHz和温度的周期性变化下，测量laurdan标记的脂质体的广义极化，表征了磷脂的相变行为。

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《Romanian Journal of Biophysics》 |2012年第2期|共9页
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MARIA-MINODORA IORDACHE; MIHAELA-GEORGETA MOISESCU; EUGENIA KOVáCS; T. SAVOPOL;
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中图分类生物物理学;
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LIPOSOMES BEHAVIOR IN ANTIBIOTICS AND RADIOFREQUENCY FIELD ENVIRONMENT

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