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Nanotoxicology and Exposure in the Occupational Setting

机译:纳米毒理学和职业环境中的暴露

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Nanotechnology refers to the ability to control the composition of molecules and atoms within the range of 1.00 - 100 nm. At this scale, many materials exhibit novel properties when compared with their micro or macro-sized equivalents, including, for example, chemical reactivity, strength, mobility and solubility. Nanoparticles are prime candidates for toxicity because they possess a much greater surface to volume ratio (i.e. the surface area compared to the volume) than larger particles of that same material; they can have biopersistance and higher oxidant capacity, penetrate epithelium and reach interstitial pulmonary region. In an industrial setting, workers may present the main exposure risk potential among humans, and they may be involved in the entire product life cycle. There are needs to protect public and environmental health and safety. Currently, no standards or regulations exist that apply or refer specifically to nanomaterials impacts.
机译:纳米技术是指将分子和原子的组成控制在1.00-100 nm范围内的能力。在这种规模下,许多材料与它们的微观或宏观等价物相比具有新颖的特性,包括例如化学反应性,强度,迁移率和溶解性。纳米粒子是毒性的主要候选者,因为它们比相同材料的较大粒子具有更大的表面积与体积之比(即表面积与体积之比)。它们具有生物持久性和较高的氧化能力,可以穿透上皮并到达肺间质区域。在工业环境中,工人可能会表现出人类潜在的主要暴露风险,并且他们可能会参与整个产品生命周期。需要保护公众和环境的健康与安全。当前,不存在适用或专门涉及纳米材料影响的标准或法规。

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