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首页> 外文期刊>Open Journal of Ophthalmology >Corneal Cross Linking with Riboflavin for Progressive Keratoconus in Paediatric Eyes
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Corneal Cross Linking with Riboflavin for Progressive Keratoconus in Paediatric Eyes

机译：角膜交联与核黄素治疗小儿进行性圆锥角膜

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Purpose: To report visual, refractive and topographic outcomes after corneal collagen crosslinking (CXL) for progressive keratoconus in paediatric eyes. Methods: In this prospective interventional study, twenty eyes of eighteen patients with progressive keratoconus were included. All eyes underwent CXL with riboflavin after documented progression of the disease. Informed, written consent was taken from the parents of the patients. The patients were followed up for 6 months. Complete ophthalmic examination and Scheimpflug imaging were performed at each visit. Reduction of the mean refractive cylinder, and corneal flattening were the main outcome measures. Results: The mean age of the patients was 13.55 years, (range: 9 - 16 yrs). The mean refractive cylinder reduced from a preoperative value of -5.26D to -4.66D (p = 0.10), -4.31D (p = 0.009), and, -4.10D (p = 0.003) at one, three and six months (postoperative) respectively. The mean average K value increased from 51.88D to 52.18D (p = 0.64) at one month postoperatively and reduced thereafter to 51.28D (p = 0.32) and 51.54D (p = 0.02) at three and six months respectively. Thinnest pachymetry reduced very significantly from a mean preoperative value of 459.15 μm to 400.8 μm (p
机译：目的：报告角膜胶原交联（CXL）后小儿眼睛进行性圆锥角膜的视觉，屈光和地​​形学结果。方法：在这项前瞻性干预研究中，纳入了18例进行性圆锥角膜患者的20只眼。记录到疾病的进展后，所有的眼睛都接受了核黄素的CXL治疗。知情的，书面的同意书来自患者的父母。随访6个月。每次访视时都要进行完整的眼科检查和Scheimpflug成像。减少平均屈光度数和角膜变平是主要的预后指标。结果：患者的平均年龄为13.55岁（范围：9-16岁）。在1、3、6个月时，平均屈光度数从术前值-5.26D降至-4.66D（p = 0.10），-4.31D（p = 0.009）和-4.10D（p = 0.003）（术后）。术后1个月，平均K值从51.88D增加到52.18D（p = 0.64），此后分别在3个月和6个月时分别降至51.28D（p = 0.32）和51.54D（p = 0.02）。最薄的测厚法从术前的平均术前值459.15μm显着降低到400.8μm（p

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