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首页> 外文期刊>Oman Journal of Ophthalmology >Comparison of relation between visual function index and retinal nerve fiber layer structure by optical coherence tomography among primary open angle glaucoma and primary angle closure glaucoma eyes
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Comparison of relation between visual function index and retinal nerve fiber layer structure by optical coherence tomography among primary open angle glaucoma and primary angle closure glaucoma eyes

机译:光学相干断层扫描在原发性开角型青光眼和原发性闭角型青光眼中的视觉功能指标与视网膜神经纤维层结构的关系比较

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摘要

Purpose:To compare the visual field index (VFI) in primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) eyes, and to study the correlation with disc variables on optical coherence tomography (OCT) in all stages of severity.Materials and Methods:Thirty POAG and PACG underwent Humphrey visual field 24-2 along with detailed examination. They also underwent stratus OCT imaging of the optic nerve and retinal nerve fiber layer (RNFL). The correlation of VFI with RNFL thickness was compared in POAG and PACG.Results:The VFI significantly differed between POAG and PACG, with POAG eyes apparently having a better VFI at all severities of glaucoma. There were statistically significant differences in the superior max (Smax) and inferior max (Imax) in early and moderate POAG and PACG eyes. In early and moderate glaucoma, multivariate regression showed that maximum correlation of the VFI was seen with the mean deviation (b = 1.7, P < 0.001), average and superior RNFL thickness (b = 2.1, P < 0.001 and b = 1.8, P = 0.03, respectively), and age (b = 0.7, P = 0.04); while no correlation was seen with intraocular pressure (IOP), axial length, sex, or other clinical variables. VFI did not correlate well with RNFL thickness or other disc variables on OCT in severe glaucoma.Conclusion:VFI may not serve as a useful indicator of visual function in severe glaucoma. More useful indicators are required to monitor glaucoma patients with severe damage.
机译:目的:比较原发性开角型青光眼(POAG)和原发性闭角型青光眼(PACG)眼睛的视野指数(VFI),并研究严重度各个阶段与光学相干断层扫描(OCT)的椎间盘变量的相关性。材料与方法:30头POAG和PACG接受汉弗莱视野24-2并进行详细检查。他们还对视神经和视网膜神经纤维层(RNFL)进行了层状OCT成像。结果:在POAG和PACG中,VFI与RNFL厚度的相关性显着不同。在所有严重程度的青光眼中,POAG眼均具有更好的VFI。早期和中度POAG和PACG眼的上最大(Smax)和下最大(Imax)在统计学上有显着差异。在早期和中度青光眼中,多元回归分析显示,VFI的最大相关性与平均偏差(b = 1.7,P <0.001),RNFL厚度的平均和优越(b = 2.1,P <0.001和b = 1.8,P =分别为0.03)和年龄(b = 0.7,P = 0.04);而与眼内压(IOP),眼轴长度,性别或其他临床变量无相关性。 VFI与严重青光眼中OCT的RNFL厚度或其他椎间盘变量没有很好的相关性。结论:VFI可能不能作为严重青光眼视觉功能的有用指标。需要更多有用的指标来监测严重损害的青光眼患者。

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