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Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)

机译：肥胖与医疗资源利用：来自临床实践研究数据库（CPRD）的结果

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Summary Background/Objectives The economic burden of obesity and type 2 diabetes (T2D) rises with increasing prevalence. This study estimates the association between obesity, healthcare resource utilization (HCRU) and associated costs in individuals with/without T2D. Subjects/Methods This observational cohort study used the United Kingdom Clinical Practice Research Datalink data. Between 1 January 2011 and 31 December 2015, total HCRU costs and individual component costs (hospitalizations, general practitioner contacts, prescriptions) were calculated for individuals linked to the Hospital Episodes Statistics database with/without T2D with normal weight, overweight, class I, II, III obesity. Results A total of 396,091 individuals were included. Increasing body mass index (BMI) was associated with increased HCRU costs. At each BMI category, costs were greater for individuals with than without T2D. Relative to normal BMI, increasing BMI was positively associated with increased HCRU costs, with similar magnitude regardless of T2D. The total HCRU cost for an individual with class III obesity was 1.4‐fold (￡3,695) greater than for normal weight. Conclusion In the United Kingdom, HCRU costs were positively associated with increasing BMI, irrespective of T2D status. The combination of T2D and obesity was associated with higher HCRU costs compared with individuals of the same BMI, without T2D. These findings suggest that prioritizing weight management programmes focused specifically on individuals with obesity and T2D may be more cost‐effective than for those with obesity alone.
机译：发明背景/目的肥胖和2型糖尿病（T2D）的经济负担随着患病率的增加而增加。这项研究估计了患有或未患有T2D的个体中肥胖，医疗资源利用（HCRU）与相关成本之间的关联。受试者/方法该观察性队列研究使用了英国临床实践研究数据链数据。在2011年1月1日至2015年12月31日期间，计算了与“医院情节统计”数据库相关联的个人的HCRU总费用和个人成分费用（住院，全科医师联系，处方），这些患者有/没有T2D，体重正常，超重，I，II级三，肥胖症。结果共纳入396,091人。体重指数（BMI）增加与HCRU成本增加有关。在每个BMI类别中，有T2D的个体的成本要高于没有T2D的个体。相对于正常的BMI，BMI的增加与HCRU成本的增加呈正相关，无论T2D大小如何，其幅度均相似。患有III级肥胖的人的总HCRU费用比正常体重高1.4倍（￡ 3,695）。结论在英国，无论T2D状况如何，HCRU成本与BMI的增加呈正相关。与没有T2D的相同BMI的个体相比，T2D和肥胖的结合与更高的HCRU成本相关。这些发现表明，优先考虑专门针对肥胖和T2D患者的体重管理计划可能比单纯肥胖的人更具成本效益。

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