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Synthetic cannabinoid-related ED visit trends in Maryland using ESSENCE, 2013-2018

机译:2013-2018年使用ESSENCE在马里兰州进行的与合成大麻素相关的ED访问趋势

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Objective Develop a free text query to track synthetic cannabinoid-related ED visits. Assess trends in synthetic cannabinoid use from 2013-2018 using spatial and time-series analysis. Introduction Maryland utilizes ESSENCE for identification of emerging public health threats, including non-fatal overdoses. Synthetic cannabinoids are heterogeneous psychoactive compounds identified as substances of abuse.[1] In March 2018, the Illinois Department of Public Health received reports of unexplained bleeding in patients who reported using these products.[2] As a result, CDC initiated coordination of national surveillance activities for possible cases of coagulopathy associated with synthetic cannabinoids use. By May 2018, state health departments reported 202 cases, including five deaths. [3] On April 3, 2018, Maryland reported its index case - a female in her 20’s who presented to an ED with nausea, blood in her stool, vaginal bleeding, bruising, an elevated internal normalized ratio ( 12.2), and bleeding oral ulcers after quitting use of a synthetic cannabinoid. She was successfully treated with Vitamin K. The first reported mortality in a Maryland resident was a male in his 30’s who called EMS for fever and blood in his urine but subsequently went into cardiac arrest and was unable to be resuscitated. The patient was known to use synthetic cannabinoids. Brodifacoum exposure was confirmed by laboratory testing. As of September 2018, the Maryland Poison Control Center had received reports of 43 cases, and 3 deaths linked to the outbreak. Methods To support surveillance and timeliness of synthetic cannabinoids reporting, we developed a case definition by conducting key word searches to identify terms/phrases used by providers in Maryland ED’s to document synthetic cannabinoid visits.
机译:目的开发一个免费的文本查询来跟踪与合成大麻素相关的ED访问。使用空间和时间序列分析评估2013年至2018年合成大麻的使用趋势。简介马里兰州利用ESSENCE识别新兴的公共卫生威胁,包括非致命的药物过量。合成大麻素是被鉴定为滥用药物的异类精神活性化合物。[1] 2018年3月,伊利诺伊州公共卫生部收到报告称使用这些产品的患者出现无法解释的出血。[2]结果,疾病预防控制中心启动了国家监测活动的协调,以应对与合成大麻素使用相关的凝血病病例。截至2018年5月,国家卫生部门报告了202例病例,包括5例死亡。 [3] 2018年4月3日,马里兰州报告了其索引病例-一名20多岁的女性,她向ED表现出恶心,粪便流血,阴道流血,青紫,内部正常比升高(> 12.2)和出血停止使用合成大麻素后出现口腔溃疡。她已成功接受维生素K治疗。据报道,这名在马里兰州居民中的首次死亡是30多岁的男性,他因发烧和尿液中的血液而被称为EMS,但随后因心脏骤停而无法复苏。已知该患者使用合成大麻素。通过实验室测试确认了溴地衣藻的暴露。截至2018年9月,马里兰州毒物控制中心已收到43起病例的报告,其中3例死亡与爆发有关。方法为了支持合成大麻素报告的监视和及时性,我们通过进行关键词搜索来识别马里兰州ED的提供者用来记录合成大麻素访问的术语/短语,从而制定了案例定义。

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