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Successful Treatment of Spine Fracture for Diffuse Idiopathic Skeletal Hyperostosis with Teriparatide—A Report of Two Cases

机译:特立帕肽成功治疗弥漫性特发性骨质增生症脊柱骨折2例

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We experienced 2 cases of spinal fracture in patients aged 80 years or older with diffuse idiopathic skeletal hyperostosis (DISH). Since they decided not to undergo surgical treatment, we provided conservative treatment with teriparatide. There has been no previous study on teriparatide for spine fracture in DISH. This is the first report of the successful use of teriparatide to treat spine fracture in DISH without surgical intervention. Our patients were treated with teriparatide for 8-9 months after diagnosis of the fracture. Union was obtained in two cases and no adverse events were observed during treatment. Our report showed that teriparatide could be an alternative to conventional intervention in spinal fracture of DISH.
机译:在80岁或以上的弥漫性特发性骨骼肥大症(DISH)患者中,我们经历了2例脊柱骨折病例。由于他们决定不接受手术治疗,因此我们提供了特立帕肽的保守治疗。以前没有关于特立帕肽治疗DISH脊柱骨折的研究。这是首次成功使用特立帕肽治疗DISH脊柱骨折的报道,无需手术干预。诊断骨折后,我们的患者接受特立帕肽治疗8-9个月。两例患者均获得了愈合,在治疗期间未观察到不良事件。我们的报告表明,teriparatide可以替代DISH脊柱骨折的常规干预。

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