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首页> 外文期刊>Open Journal of Urology >Comparison of Fusion Rates between Autologous Iliac Bone Graft and Calcium Sulfate with Laminectomy Bone Chips in Multilevel Posterolateral Spine Fusion
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Comparison of Fusion Rates between Autologous Iliac Bone Graft and Calcium Sulfate with Laminectomy Bone Chips in Multilevel Posterolateral Spine Fusion

机译：自体lia骨移植与硫酸钙与椎板切除术骨片在多级后外侧脊柱融合术中的融合率比较

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Multilevel lumbar fusion usually requires a large quantity of iliac crest bone graft but the supply is usually insufficient, so an alternative bone graft substitute for autograft is needed. This prospective study investigated the efficacy of calcium sulfate by comparing the fusion rates between the experimental material (calcium sulfate pellets with bone chips from laminectomy) and autologous iliac bone graft in long segment (three-or four-level) lumbar and lumbosacral posterolateral fusion. Forty-five patients with degenerative scoliosis or spondylolisthesis received multilevel spine fusion and decompression. The experimental material of calcium sulfate pellets with decompression bone chips was placed on the experimental side and the iliac crest bone graft was placed on the control side. The fusion status was assessed radiographically at three-month intervals, and solid fusion was defined as a clear continuous intertransverse bony bridge at all levels. The average follow-up period was 34.4 months. Twenty-nine (64.4%) patients showed solid fusion on the experimental side and 39 (86.7%) patients on the control side. The overall fusion rate was 86.7%. A statistically significant relation was found between the two sides with the Kappa coefficient of agreement of 0.436. Compared to the control side, the fusion rate of experimental side is significantly reduced (p = 0.014). The fusion ability of autograft is higher than the experimental material in multilevel lumbar posterolateral fusion. However, the overall fusion rate of calcium sulfate pellets is improved, compared with previously reported rates, which suggested that such material may be considered as an acceptable bone graft extender.
机译：多级腰椎融合术通常需要大量of骨骨移植，但供应通常不足，因此需要替代自体骨的替代骨移植。这项前瞻性研究通过比较实验材料（带椎板切除术的硫酸钙小丸加骨碎片）与自体骨移植在长节段（三级或四级）腰椎和腰后外侧融合中的融合率，研究了硫酸钙的疗效。四十五例退行性脊柱侧凸或脊柱滑脱患者接受了多级脊柱融合和减压术。将带有减压骨屑的硫酸钙药丸的实验材料置于实验侧，将c骨植骨置于对照侧。每三个月进行影像学评估，评估融合状态，并将固体融合定义为所有水平的透明连续横突间骨桥。平均随访时间为34.4个月。 29例（64.4％）患者在实验侧显示固体融合，而39例（86.7％）在对照侧显示融合。总融合率为86.7％。发现双方之间的统计意义显着，卡帕协议系数为0.436。与对照组相比，实验组的融合率显着降低（p = 0.014）。在多级腰椎后外侧融合中，自体移植物的融合能力高于实验材料。然而，与先前报道的速率相比，硫酸钙丸粒的总融合速率得到了改善，这表明这种材料可以被认为是可接受的骨移植增量剂。

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