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首页> 外文期刊>Open Journal of Urology >Mapping the EQ-5D-5L Utility Scores: A Pilot Study in Orthopaedic Patients
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Mapping the EQ-5D-5L Utility Scores: A Pilot Study in Orthopaedic Patients

机译：绘制EQ-5D-5L效用评分图：骨科患者的一项初步研究

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Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor; it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT; they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.
机译：目的：本研究的目的是研究LE CAT，PROMIS PF CAT，抑郁CAT或疼痛CAT是否可以用作EQ-5D-5L的代理。背景：患者报告的结果措施已成为医师了解治疗和护理的有效性和价值的重要工具。方法：这项研究于2012年在大学骨科诊所对116例服用EQ-5D-5L的患者和许多患者报告的结局仪器进行了研究。进行了回归分析以根据LE CAT，PROMIS PF CAT，Depression CAT和Pain CAT预测EQ-5D-5L指数得分。结果：所有单独或组合的预测变量均能显着预测EQ-5D-5L指数得分（p <0.0001）。 LE CAT是最好的预测器。仅此一项就占了EQ-5D-5L变异性的37％。当结合患者报告的结局指标时，最好的预测模型是LE CAT，Depression CAT和Pain CAT。他们解释了EQ-5D-5L方差的43.9％。结论：这些发现提供了令人鼓舞的消息，即LE CAT，PF CAT，抑郁CAT和疼痛CAT可以单独使用，也可以组合使用作为EQ-5D-5L的替代产品。研究人员可以选择将这些患者报告的结局指标用于经济评估和医学干预研究。

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