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Lectins: An Analysis

机译:凝集素:分析

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摘要

Introduction: The study of lectins began with the work of Hermann Stillmark in the year 1888. Lectins are carbohydrate- binding proteins of nonimmune origin and find application in diagnostic pathology. Objectives: Recent research work shows a remarkable devel- opment in lectin science. This comprehensive review tries to emphasize the historical aspects, biological sources, classifica- tion, applications, and recent advances of lectins. Materials and methods: Electronic database searches for published literature were performed. The following electronic databases with no language and publication date restrictions were searched: MEDLINE (via Ovid and PubMed), EMBASE (via Ovid), the Cochrane Oral Health Group's Trials Register, and CENTRAL. Results: Lectins have been proven to be effective in in vitro trials for combating many medical conditions like cancer, auto- immune disorders, etc. Conclusion: Lectins could be the next generation therapy if efficient research work is contributed to the understanding of their behavior.
机译:简介:凝集素的研究始于1888年Hermann Stillmark的研究。凝集素是非免疫起源的碳水化合物结合蛋白,可用于诊断病理学。目标:最近的研究工作表明,凝集素科学发展显着。这项全面的综述试图强调凝集素的历史方面,生物学来源,分类,应用和最新进展。材料和方法:进行电子数据库检索已发表的文献。搜索了以下无语言和出版日期限制的电子数据库:MEDLINE(通过Ovid和PubMed),EMBASE(通过Ovid),Cochrane口腔健康小组的试验注册和CENTRAL。结果:凝集素在体外试验中被证明可有效对抗多种医学疾病,例如癌症,自身免疫性疾病等。结论:如果有效的研究工作有助于了解凝集素的行为,凝集素可以成为下一代疗法。

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